Evidence map›Paper›PMID 29970005›Full record

ArticleBMC geriatrics2018

Medication review versus usual care to improve drug therapies in older inpatients not admitted to geriatric wards: a quasi-experimental study (RASP-IGCT).

Lorenz Van der Linden, Julie Hias, Lisa Dreessen, Koen Milisen, Johan Flamaing, Isabel Spriet, Jos Tournoy

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02165618 (Rationalisation of Polypharmacy by the Geriatric Consultation Team Using the RASP List), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02165618 nacompletednot on this map

Rationalisation of Polypharmacy by the Geriatric Consultation Team Using the RASP List: a Pilot Study

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2014 to 2014Enrolled60ConditionsIatrogenic DiseaseArmsMedication review, based on but not limited to the RASP list
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lorenz Van der LindenPharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium. lorenz.vanderlinden@uzleuven.be.ORCID 0000-0001-5195-1891
Julie HiasPharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Lisa DreessenDepartment of Geriatric Medicine, University Hospital of Brussels, Brussels, Belgium.
Koen MilisenDepartment of Public Health and Primary Care, Health Services and Nursing Research, KU Leuven, Louvain, Belgium.
Johan FlamaingDepartment of Geriatric Medicine, University Hospitals Leuven, Louvain, Belgium.
Isabel SprietPharmacy Department, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium.
Jos TournoyDepartment of Geriatric Medicine, University Hospitals Leuven, Louvain, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterdisciplinary geriatric consultation teams (IGCT) are regularly requested to provide comprehensive geriatric assessments in older inpatients. Our primary aim was to evaluate whether medication reviews increased the number of IGCT-provided drug-related recommendations. Secondary aims were to reduce the number of potentially inappropriate medications (PIMs), and to identify the acceptance rate of and determinants for the number of recommendations.

methodsA before-after study was performed in older inpatients not admitted to acute geriatric wards. The before cohort received usual care (UC); the after cohort was subjected to the intervention (I), consisting of a systematic medication review, based on but not limited to the RASP (Rationalization of Home Medication by an Adjusted STOPP in Older Patients) list. The primary outcome measure was the number of IGCT-provided drug-related recommendations. Age, sex, Charlson Comorbidity Index, creatinine clearance and serum creatinine were ascertained upon enrolment. Following variables were determined on admission and at discharge: number of drugs and number as well as type of RASP-identified PIMs. Acceptance by ward-based physicians was also determined. Poisson regression was performed to identify determinants for the primary outcome measure.

resultsFifty-nine participants were enrolled (n

conclusionsA structured medication review as part of usual IGCT care may contribute to an increased detection of drug-related problems and help to further reduce polypharmacy in older inpatients, not admitted to acute geriatric care wards.

trial registrationNCT02165618 , retrospectively registered June 17, 2014.

Indexed as

InpatientsAgedAged, 80 and overFemaleHealth Services for the AgedHospitalizationHospitalsHumansInappropriate PrescribingMalePolypharmacyPotentially Inappropriate Medication ListRetrospective StudiesDrug useIGCTMedication reviewOlder inpatientsPIMPolypharmacyScreening tool

Identifiers

PMID29970005
PMCPMC6029069
OpenAlexW2810179111

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.