Trial reportAmerican journal of Alzheimer's disease and other dementias2018
Sex Differences in the Neuropsychiatric Symptoms of Patients With Alzheimer's Disease.
Trial report in American journal of Alzheimer's disease and other dementias, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03208049 (Predictors of Response to Insomnia Treatments for Gulf War Veterans), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predictors of Response to Insomnia Treatments for Gulf War Veterans
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Sex differences in neuropsychiatric symptoms in Alzheimer's disease dementia: a meta-analysis.Alzheimer's research & therapy · 2022Pooled it
- Factor Analysis of the Short-Form Cohen-Mansfield Agitation Inventory and the Measurement Invariance by Gender.Journal of nursing measurement · 2021Trial
- Structural signature of plasma proteins classifies the status of Alzheimer's disease.Nature aging · 2026Article
- Associations of living alone and loneliness with neuropsychiatric symptoms in individuals with mild cognitive impairment: A retrospective cross-sectional study.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Uncovering sex patterns in BPSD among home-care patients: longitudinal findings from a population-based registry - digital dementia registry Bavaria.Frontiers in psychiatry · 2026Article
- Specific cognitive impairment predicts the neuropsychiatric symptoms in patient with mild cognitive impairment.Aging clinical and experimental research · 2025Article
- Sex-Specific Adaptations in Alzheimer's Disease and Ischemic Stroke: A Longitudinal Study in Male and Female APPLife (Basel, Switzerland) · 2025Article
- Neuropsychiatric symptoms in mild cognitive impairment and early Alzheimer's disease: Clinical pattern and diagnostic implications.AIMS neuroscience · 2025Review
- Caregiving burdens of task time and task difficulty among paid and unpaid caregivers of persons living with dementia.Frontiers in public health · 2025Article
- Behavioral and Psychological Symptoms of Dementia and Mortality Risk Among People With Cognitive Impairment: An 8-year Longitudinal Study From the NCGG-STORIES.Journal of epidemiology · 2024Article
- Cognitive Performance and Incident Alzheimer's Dementia in Men Versus Women.The journal of prevention of Alzheimer's disease · 2024Article
- Malnutrition and neuropsychiatric symptoms in dementia: the Cache County Dementia Progression Study.International psychogeriatrics · 2023Observational
- A brainstem to circadian system circuit links Tau pathology to sundowning-related disturbances in an Alzheimer's disease mouse model.Nature communications · 2023Article
- White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases.Alzheimer's research & therapy · 2023Article
- Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease.Neurobiology of aging · 2023Article
- Neuropsychiatric Symptoms as Indicators of Fall Risk in Geriatric Inpatients.Medicina (Kaunas, Lithuania) · 2023Article
- Associations between neuropsychiatric symptoms and incident Alzheimer's dementia in men versus women.Journal of neurology · 2023Article
- Metabolic changes in the plasma of mild Alzheimer's disease patients treated with Hachimijiogan.Frontiers in pharmacology · 2023Article
- The role of sex differences in depression in pathologically defined Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
- Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
Abstract
The aim of this study was to describe sex differences in neuropsychiatric symptoms (NPSs) in patients with Alzheimer's disease (AD). Baseline scores on the Cohen-Mansfield Agitation Inventory, Neurobehavioral Rating Scale-Agitation subscale, and the Neuropsychiatric Inventory from patients with AD enrolled in a multicenter trial of citalopram for the treatment of agitation were analyzed. We found not only that patients with AD having agitation were likely to exhibit many other NPSs but also that the women in this study were more likely to exhibit a broader range of NPS than were the men. These results suggest greater heterogeneity in the clinical presentation of women compared to men, and thus in the potential targets for treatment in these patients. Further characterization of sex differences in NPS can inform future efforts aimed at establishing subtypes of patients for whom various treatment approaches will be most appropriate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.