ArticleAnnals of pediatric endocrinology & metabolism2018
Etiological trends in male central precocious puberty.
Article in Annals of pediatric endocrinology & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Early-onset juvenile nasopharyngeal angiofibroma (JNA): a systematic review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023Pooled it
- Idiopathic Central Precocious Puberty in Boys: Results from a National Portuguese Cohort.Hormone research in paediatrics · 2026Article
- Central Precocious Puberty in Males, GnRH Analog Treated or Untreated, Did Not Impact Fertility and Health in Midadulthood.The Journal of clinical endocrinology and metabolism · 2025Article
- Central precocious puberty in boys; diagnosis, treatment and follow-up: a nation-wide study.Endocrine · 2025Article
- Correlation analysis of pituitary morphometry in boys with idiopathic central precocious puberty or early puberty: implications for diagnosis.Translational pediatrics · 2025Article
- Prevalence of organic central precocious puberty in males: criteria for a high index of suspicion.Endocrine connections · 2025Article
- Central Precocious Puberty in Italian Boys: Data From a Large Nationwide Cohort.The Journal of clinical endocrinology and metabolism · 2024Article
- Central precocious puberty - etiology with particular consideration of neurological causes.Archives of medical science : AMS · 2024Article
- Precocious puberty under stressful conditions: new understanding and insights from the lessons learnt from international adoptions and the COVID-19 pandemic.Frontiers in endocrinology · 2023Review
- Central precocious puberty in Sudan: 10 years' experience of paediatric endocrinology centres.Sudanese journal of paediatrics · 2023Article
- Commentary on "Pathological brain lesions in girls with central precocious puberty at initial diagnosis in Southern Vietnam".Annals of pediatric endocrinology & metabolism · 2022Article
- An increasing tendency of precocious puberty among Korean children from the perspective of COVID-19 pandemic effect.Frontiers in pediatrics · 2022Article
- A review of the genetics and epigenetics of central precocious puberty.Frontiers in endocrinology · 2022Review
- Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty.Annals of pediatric endocrinology & metabolism · 2021Article
- Precocious Puberty in Boys: A Study Based on Five Years of Data from a Single Center in Northern ChinaJournal of clinical research in pediatric endocrinology · 2021Article
- [Clinical guidelines «Precocious puberty»].Problemy endokrinologii · 2021Article
- Enrichment analyses of diseases and pathways associated with precocious puberty using PrecocityDB.Scientific reports · 2021Article
- Association of maxillary dental developmental abnormality with precocious puberty: a case-control study.Maxillofacial plastic and reconstructive surgery · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn the present study, the etiological trends in male central precocious puberty (CPP) were examined, and annual distribution was evaluated.
methodsSeventy-one male CPP subjects who started puberty before 9 years of age were included in this study. All individuals were diagnosed as having CPP at Samsung Medical Center between 2001 and 2016. Chronological age at puberty onset, diagnosis of CPP, bone age, weight (kg), height (cm), puberty stage, brain magnetic resonance imaging findings, testosterone level, basal gonadotropin level, and gonadotropin level after gonadotropin releasing hormone stimulation were analyzed.
resultsThe 71 patients were divided into 2 groups: idiopathic (group I) and organic (group II) when the lesion was identified as associated with the central nervous system (CNS) or when the patient received chemotherapy for non-CNS tumors before CPP diagnosis, respectively. Forty-four cases (62%) were idiopathic, and 27 (38%) were organic. The proportion of idiopathic CPP was higher than that of organic CPP during the study period. In 51.9% of organic cases, puberty started before 8 years of age, whereas it started after that age in 93.2% of the idiopathic cases.
conclusionIn the present study, among all male CPP cases, 62% were idiopathic. The probability of idiopathic CPP prevalence was higher in males when the puberty onset was after 8 years of age with no history of cranial radiotherapy or chemotherapy.
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