ArticlePLoS biology2018
A revised understanding of Tribolium morphogenesis further reconciles short and long germ development.
Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 43 citations in OpenAlex.
- Sixteen isotropic 3D fluorescence live-imaging datasets of gastrulation in the red flour beetle Tribolium castaneum (Coleoptera: Tenebrionidae).Scientific data · 2026Article
- Long-term fluorescence live imaging of honeybee embryos using light sheet fluorescence microscopy and halocarbon-based liquids.Biology open · 2025Article
- Embryogenesis in Myrmicine Ants Combines Features of Short Germ-Band Development With a Progressive Mode of Segmentation.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Article
- Extraembryonic tissue in chelicerates: a review and outlook.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- The extended analogy of extraembryonic development in insects and amniotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Dynamics of maternal gene expression in Rhodnius prolixus.Scientific reports · 2022Article
- Virtual spherical-shaped multicellular platform for simulating the morphogenetic processes of spider-like body axis formation.Frontiers in cell and developmental biology · 2022Article
- The neuroblast timer gene nubbin exhibits functional redundancy with gap genes to regulate segment identity in Tribolium.Development (Cambridge, England) · 2021Article
- Time and space in segmentation.Interface focus · 2021Article
- Homology of process: developmental dynamics in comparative biology.Interface focus · 2021Article
- Panarthropod tiptop/teashirt and spalt orthologs and their potential role as "trunk"-selector genes.EvoDevo · 2021Article
- Article
- Functional analysis of sense organ specification in the Tribolium castaneum larva reveals divergent mechanisms in insects.BMC biology · 2021Article
- A corset function of exoskeletal ECM promotes body elongation in Drosophila.Communications biology · 2021Article
- Spatiotemporal variation in cell proliferation patterns during arthropod axial elongation.Scientific reports · 2021Article
- Article
- Article
- The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning.eLife · 2019Article
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
In Drosophila melanogaster, the germband forms directly on the egg surface and solely consists of embryonic tissue. In contrast, most insect embryos undergo a complicated set of tissue rearrangements to generate a condensed, multilayered germband. The ventral side of the germband is embryonic, while the dorsal side is thought to be an extraembryonic tissue called the amnion. While this tissue organisation has been accepted for decades and has been widely reported in insects, its accuracy has not been directly tested in any species. Using live cell tracking and differential cell labelling in the short germ beetle Tribolium castaneum, I show that most of the cells previously thought to be amnion actually give rise to large parts of the embryo. This process occurs via the dorsal-to-ventral flow of cells and contributes to germband extension (GBE). In addition, I show that true 'amnion' cells in Tribolium originate from a small region of the blastoderm. Together, my findings show that development in the short germ embryos of Tribolium and the long germ embryos of Drosophila is more similar than previously proposed. Dorsal-to-ventral cell flow also occurs in Drosophila during GBE, and I argue that the flow is driven by a conserved set of underlying morphogenetic events in both species. Furthermore, the revised Tribolium fate map that I present is far more similar to that of Drosophila than the classic Tribolium fate map. Lastly, my findings show that there is no qualitative difference between the tissue structure of the cellularised blastoderm and the short/intermediate germ germband. As such, the same tissue patterning mechanisms could function continuously throughout the cellularised blastoderm and germband stages, and easily shift between them over evolutionary time.
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