ArticlePloS one2018
Genetic and biological characterization of H9N2 avian influenza viruses isolated in China from 2011 to 2014.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Pooled it
- Article
- Autophagy in emerging and highly concerned severe zoonotic infectious diseases.Frontiers in immunology · 2026Review
- Review of respiratory syndromes in poultry: pathogens, prevention, and control measures.Veterinary research · 2025Review
- Effect of Chicken AvBD11 on the Cytokines in the Erythrocytes of Chickens Infected with the Avian Influenza Virus of the Subtype H9N2.Animals : an open access journal from MDPI · 2025Article
- Modelling the transmission dynamics of H9N2 avian influenza viruses in a live bird market.Nature communications · 2024Article
- HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding.Frontiers in veterinary science · 2024Article
- The emergence of new antigen branches of H9N2 avian influenza virus in China due to antigenic drift on hemagglutinin through antibody escape at immunodominant sites.Emerging microbes & infections · 2023Article
- Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail (Journal of virology · 2023Article
- Antigenic Evolution Characteristics and Immunological Evaluation of H9N2 Avian Influenza Viruses from 1994-2019 in China.Viruses · 2022Article
- Coinfection of Chickens with H9N2 and H7N9 Avian Influenza Viruses Leads to Emergence of Reassortant H9N9 Virus with Increased Fitness for Poultry and a Zoonotic Potential.Journal of virology · 2022Article
- G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment.BMC veterinary research · 2021Article
- A risk marker of tribasic hemagglutinin cleavage site in influenza A (H9N2) virus.Communications biology · 2021Article
- Full-length genome sequences of the first H9N2 avian influenza viruses isolated in the Northeast of Algeria.Virology journal · 2020Article
- H9 Influenza Viruses: An Emerging Challenge.Cold Spring Harbor perspectives in medicine · 2020Review
- Adaptation of H9N2 Influenza Viruses to Mammalian Hosts: A Review of Molecular Markers.Viruses · 2020Review
- Comparison of pathogenicity of subtype H9 avian influenza wild-type viruses from a wide geographic origin expressing mono-, di-, or tri-basic hemagglutinin cleavage sites.Veterinary research · 2020Article
- Article
- Impact of the variations in potential glycosylation sites of the hemagglutinin of H9N2 influenza virus.Virus genes · 2019Article
- The evolution and genetic diversity of avian influenza A(H9N2) viruses in Cambodia, 2015 - 2016.PloS one · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genotypes of the H9N2 avian influenza viruses have changed since 2013 when almost all H9N2 viruses circulating in chickens in China were genotype 57 (G57) with the fittest lineage of each gene. To characterize the H9N2 variant viruses from 2011 to 2014, 28 H9N2 influenza viruses were isolated from live poultry markets in China from 2011-2014 and were analyzed by genetic and biological characterization. Our findings showed that 16 residues that changed antigenicity, two potential N-linked glycosylation sites, and one amino acid in the receptor binding site of the HA protein changed significantly from 2011-2014. Moreover, the HA and NA genes in the phylogenetic tree were mainly clustered into two independent branches, A and B, based on the year of isolation. H9N2 virus internal genes were related to those from the human-infected avian influenza viruses H5N1, H7N9, and H10N8. In particular, the NS gene in the phylogenetic tree revealed genetic divergence of the virus gene into three branches labeled A, B, and C, which were related to the H9N2, H10N8, and H7N9 viruses, respectively. Additionally, the isolates also showed varying levels of infection and airborne transmission. These results indicated that the H9N2 virus had undergone an adaptive evolution and variation from 2011-2014.
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