Evidence map›Paper›PMID 29969293›Full record

Trial reportJournal of child and adolescent psychopharmacology2018

Group Cognitive Behavioral Therapy and Attention Bias Modification for Childhood Anxiety Disorders: A Factorial Randomized Trial of Efficacy.

Giovanni A Salum, Circe S Petersen, Rafaela B Jarros, Rudineia Toazza, Diogo DeSousa, Lidiane Nunes Borba, Stela Castro, Julia Gallegos, Paula Barrett, Rany Abend and 4 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of child and adolescent psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Review
  9. Article
  10. Attentional biases in human anxiety.Neuroscience and biobehavioral reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giovanni A Salum1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .
Circe S Petersen2 Center of Psychological Studies on at Risk Populations, Institute of Psychology , Porto Alegre, Brazil .
Rafaela B Jarros1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .
Rudineia Toazza1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .
Diogo DeSousa1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .
Lidiane Nunes Borba1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .
Stela Castro3 Institute of Mathematics, Federal University of Rio Grande do Sul , Porto Alegre, Brazil .
Julia Gallegos4 Department of Psychology, University of Monterrey , Monterrey, Mexico .
Paula Barrett5 Faculty of Social and Behavioral Sciences, School of Education, The University of Queensland , Brisbane, Australia .
Rany Abend6 School of Psychological Sciences, Tel Aviv University , Tel Aviv, Israel .
Yair Bar-Haim6 School of Psychological Sciences, Tel Aviv University , Tel Aviv, Israel .
Daniel S Pine7 Emotion and Development Branch, Intramural Research Program, National Institute of Mental Health , Bethesda, Maryland.
Silvia H Koller2 Center of Psychological Studies on at Risk Populations, Institute of Psychology , Porto Alegre, Brazil .
Gisele G Manfro1 Child and Adolescent Anxiety Program, Department of Psychiatry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil .

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
6 · The paper itself

Abstract

backgroundThe objective of this study is to assess group differences in symptom reduction between individuals receiving group cognitive behavioral therapy (G-CBT) and attention bias modification (ABM) compared to their respective control interventions, control therapy (CT), and attention control training (ACT), in a 2 × 2 factorial design.

methodsA total of 310 treatment-naive children (7-11 years of age) were assessed for eligibility and 79 children with generalized, separation or social anxiety disorder were randomized and received G-CBT (n = 42) or CT (n = 37). Within each psychotherapy group, participants were again randomized to ABM (n = 38) or ACT (n = 41) in a 2 × 2 factorial design resulting in four groups: G-CBT + ABM (n = 21), G-CBT + ACT (n = 21), CT + ABM (n = 17), and CT + ACT (n = 20). Primary outcomes were responder designation as defined by Clinical Global Impression-Improvement (CGI-I) scale (≤2) and change on the Pediatric Anxiety Rating Scale (PARS).

resultsThere were significant improvements of symptoms in all groups. No differences in response rates or mean differences in PARS scores were found among groups: G-CBT + ABM group (23.8% response; 3.9 points, 95% confidence interval [CI] -0.3 to 8.1), G-CBT + ACT (42.9% response; 5.6 points, 95% CI 2.2-9.0), CT + ABM (47.1% response; 4.8 points 95% CI 1.08-8.57), and CT + ACT (30% response; 0.8 points, 95% CI -3.0 to 4.7). No evidence or synergic or antagonistic effects were found, but the combination of G-CBT and ABM was found to increase dropout rate.

conclusionsWe found no effect of G-CBT or ABM beyond the effects of comparison groups. Results reveal no benefit from combining G-CBT and ABM for anxiety disorders in children and suggest potential deleterious effects of the combination on treatment acceptability.

Indexed as

Attentional BiasPsychotherapy, GroupAnxiety DisordersBrief Psychiatric Rating ScaleChildCognitive Behavioral TherapyDouble-Blind MethodFemaleHumansMaleattention bias modification treatmentattention retrainingattention trainingcognitive behavioral therapyfactorialphobias

Identifiers

PMID29969293
PMCPMC6421990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.