ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2019
DEPTOR modulates activation responses in CD4
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Neuropilin-2 functions as a coinhibitory receptor to regulate antigen-induced inflammation and allograft rejection.The Journal of clinical investigation · 2025Article
- Immunomodulation by allograft endothelial cells.Frontiers in transplantation · 2025Review
- Autoimmune disease: genetic susceptibility, environmental triggers, and immune dysregulation. Where can we develop therapies?Frontiers in immunology · 2025Review
- The Role of Ubiquitin-Proteasome System (UPS) in Asthma Pathology.Journal of asthma and allergy · 2025Review
- Metformin inhibits EV71‑induced pyroptosis by upregulating DEP domain‑containing mTOR‑interacting protein.Experimental and therapeutic medicine · 2023Article
- Integrative transcriptome and proteome analyses of clear cell renal cell carcinoma develop a prognostic classifier associated with thrombus.Scientific reports · 2023Article
- Epithelial cell-derived cytokine TSLP activates regulatory T cells by enhancing fatty acid uptake.Scientific reports · 2023Article
- The potential role of T-cell metabolism-related molecules in chronic neuropathic pain after nerve injury: a narrative review.Frontiers in immunology · 2023Review
- How GRAIL controls Treg function to maintain self-tolerance.Frontiers in immunology · 2022Article
- Regulation of human mTOR complexes by DEPTOR.eLife · 2021Article
- mTOR signaling at the crossroads of environmental signals and T-cell fate decisions.Immunological reviews · 2020Review
- Next Generation Strategies for Geroprotection via mTORC1 Inhibition.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Review
- T Cell-Specific Adaptor Protein Regulates Mitochondrial Function and CD4Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Metabolic Pathways Involved in Regulatory T Cell Functionality.Frontiers in immunology · 2019Review
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
DEPTOR is an evolutionarily conserved cell-intrinsic binding partner of mTOR that functions as a negative regulator of signaling responses. In this study, we show that DEPTOR is expressed within CD4
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.