Evidence map›Paper›PMID 29968791›Full record

ArticleScientific reports2018

Development of optokinetic tracking software for objective evaluation of visual function in rodents.

Francisco Segura, Justo Arines, Ana Sánchez-Cano, Lorena Perdices, Elvira Orduna-Hospital, Lorena Fuentes-Broto, Isabel Pinilla

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. A New Optokinetic Testing Method to Measure Rat Vision.Journal of visualized experiments : JoVE · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Francisco SeguraDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain.
Justo ArinesDepartment of Applied Physics, University of Santiago de Compostela, Santiago de Compostela, Spain.
Ana Sánchez-CanoDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain.
Lorena PerdicesAragon Institute for Health Research (IIS Aragón), Zaragoza, Spain.
Elvira Orduna-HospitalAragon Institute for Health Research (IIS Aragón), Zaragoza, Spain.
Lorena Fuentes-BrotoAragon Institute for Health Research (IIS Aragón), Zaragoza, Spain.
Isabel PinillaAragon Institute for Health Research (IIS Aragón), Zaragoza, Spain. isabel.pinilla@telefonica.net.
Universidad de Zaragoza · ESInstituto de Investigación Sanitaria Aragón · ESUniversidade de Santiago de Compostela · ES

Funding

Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI13/01124
6 · The paper itself

Abstract

The aim of this study was to develop software that performs the optokinetic tracking assessment without the involvement of experimenters to increase the objectivity of the test. To check the effectiveness of the software, several videos were analyzed and the results were compared to those produced by two experimenters. Videos consisted of visual acuity and contrast sensitivity tests on normal animals and pigmented P23H rats (animal model of retinitis pigmentosa). Our software showed a reasonably high success rate: in approximately 78% of the cases, both the software program and the experimenters were in agreement, including the direction of rotation. The software detected 7% false positive cases, 10% false negative cases, and it was wrong in 5% of the cases. Decrease in visual function with age in pigmented P23H rats was observed from the first time interval, although minimum thresholds were found in visual parameters at advanced ages. We developed simple software based on current functions included in the Matlab image processing toolbox that was able to recognize, with a reasonably high percentage of success, the subtle head movements of the rodent produced when visual perception of the optokinetic optotype occurs.

Indexed as

SoftwareAnimalsEye MovementsHead MovementsModels, AnimalPhotic StimulationRatsRats, Long-EvansVision, OcularVisual Acuity

Identifiers

PMID29968791
PMCPMC6030196
OpenAlexW2810399854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.