Evidence map›Paper›PMID 29968735›Full record

ArticleScientific reports2018

Broadband (550-1350 nm) diffuse optical characterization of thyroid chromophores.

Sanathana Konugolu Venkata Sekar, Andrea Farina, Alberto Dalla Mora, Claus Lindner, Marco Pagliazzi, Mireia Mora, Gloria Aranda, Hamid Dehghani, Turgut Durduran, Paola Taroni and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sanathana Konugolu Venkata SekarPolitecnico di Milano, Dipartimento di Fisica, Milano, Italy. sanathana.konugolu@polimi.it.ORCID 0000-0003-0912-1282
Andrea FarinaConsiglio Nazionale delle Ricerche, Istituto di Fotonica e Nanotecnologie, Milano, Italy.
Alberto Dalla MoraPolitecnico di Milano, Dipartimento di Fisica, Milano, Italy.
Claus LindnerICFO-Institut de Ciències Fotòniques, Barcelona, Spain.ORCID 0000-0002-9878-037X
Marco PagliazziICFO-Institut de Ciències Fotòniques, Barcelona, Spain.
Mireia MoraIDIBAPS, Fundació Clínic per la Recerca Biomèdica, 08036, Barcelona, Spain.
Gloria ArandaIDIBAPS, Fundació Clínic per la Recerca Biomèdica, 08036, Barcelona, Spain.
Hamid DehghaniUniversity of Birmingham, School of Computer Science, Edgbaston, Birmingham, United Kingdom.
Turgut DurduranICFO-Institut de Ciències Fotòniques, Barcelona, Spain.
Paola TaroniPolitecnico di Milano, Dipartimento di Fisica, Milano, Italy.
Antonio PifferiPolitecnico di Milano, Dipartimento di Fisica, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid plays an important role in the endocrine system of the human body. Its characterization by diffuse optics can open new path ways in the non-invasive diagnosis of thyroid pathologies. Yet, the absorption spectra of tyrosine and thyroglobulin-key tissue constituents specific to the thyroid organ-in the visible to near infrared range are not fully available. Here, we present the optical characterization of tyrosine (powder), thyroglobulin (granular form) and iodine (aqueous solution) using a time domain broadband diffuse optical spectrometer in the 550-1350 nm range. Various systematic errors caused by physics of photo migration and sample inherent properties were effectively suppressed by means of advanced time domain diffuse optical methods. A brief comparison with various other known tissue constituents is presented, which reveals key spectral regions for the quantification of the thyroid absorbers in an in vivo scenario.

Indexed as

HumansIodineOptical PhenomenaSpectrum AnalysisThyroglobulinThyroid GlandThyroid NoduleTyrosineIodineThyroglobulinTyrosine

Identifiers

PMID29968735
PMCPMC6030074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.