Evidence map›Paper›PMID 29968393›Full record

ArticleCancer science2018

Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance.

Yasutaka Yamada, Takayuki Arai, Satoko Kojima, Sho Sugawara, Mayuko Kato, Atsushi Okato, Kazuto Yamazaki, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki

Abstract read
In one paragraph

Article in Cancer science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. LINCRNA01094 Promotes Renal Interstitial Fibrosis via the Mir-513b-5p/ MELK/Smad3 Axis.Endocrine, metabolic & immune disorders drug targets · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Role and mechanism ofFrontiers in pharmacology · 2024
    Article
  9. Article
  10. Article
  11. CENPF promotes the proliferation of renal cell carcinomaTranslational andrology and urology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. CLINICAL VALIDATION OF ANKRD36 MUTATIONS AS A NOVEL BIOMARKER FOR MONITORING EARLY PROGRESSION AND TIMELY CLINICAL INTERVENTIONS IN BLAST CRISIS CML.Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique · 2022
    Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yasutaka YamadaDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID http://orcid.org/0000-0002-0070-1590
Takayuki AraiDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID http://orcid.org/0000-0002-3888-9576
Satoko KojimaDepartment of Urology, Teikyo University Chiba Medical Center, Ichihara, Japan.
Sho SugawaraDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.
Mayuko KatoDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.
Atsushi OkatoDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.
Kazuto YamazakiDepartment of Pathology, Teikyo University Chiba Medical Center, Ichihara, Japan.
Yukio NayaDepartment of Urology, Teikyo University Chiba Medical Center, Ichihara, Japan.
Tomohiko IchikawaDepartment of Urology, Chiba University Graduate School of Medicine, Chiba, Japan.
Naohiko SekiDepartment of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan.

Funding

Japan Society for the Promotion of Science KAKENHI 15K10801Japan Society for the Promotion of Science KAKENHI 16H05462Japan Society for the Promotion of Science KAKENHI 16K20125Japan Society for the Promotion of Science KAKENHI 17K11160
6 · The paper itself

Abstract

In the human genome, miR-451a, miR-144-5p (passenger strand), and miR-144-3p (guide strand) reside in clustered microRNA (miRNA) sequences located within the 17q11.2 region. Low expression of these miRNAs is significantly associated with poor prognosis of patients with renal cell carcinoma (RCC) (miR-451a: P = .00305; miR-144-5p: P = .00128; miR-144-3p: P = 9.45 × 10

Indexed as

AgedCarcinoma, Renal CellCell Line, TumorCell MovementCell ProliferationFemaleHumansKidney NeoplasmsMaleMicroRNAsMiddle AgedNeoplasm InvasivenessOncogenesPrognosisRNA InterferenceRNA, Small InterferingMicroRNAsMIRN144 microRNA, humanRNA, Small InterferingSDC3 protein, humanSyndecan-3antitumormicroRNAmiR-144-5prenal cell carcinomaSDC3

Identifiers

PMID29968393
PMCPMC6125479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.