ArticleGeroScience2018
Factors that positively or negatively mediate the effects of age on working memory across the adult life span.
Article in GeroScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Encoding-related fMRI BOLD activity predicts subsequent memory for studied scenes, but not subsequent identification of perceptually similar lures.bioRxiv : the preprint server for biology · 2026Article
- Eight brain structures mediate the age-related alterations of the working memory: forward and backward digit span tasks.Frontiers in psychology · 2024Article
- Diet May Moderate the Relationship Between Arterial Stiffness and Cognitive Performance in Older Adults.Journal of Alzheimer's disease : JAD · 2022Article
- The role of cognitive reserve as mediator for addition and multiplication skills in late adulthood.Aging clinical and experimental research · 2021Article
- Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice.Journal of lipid research · 2020Article
- Executive Function and Diabetes: A Clinical Neuropsychology Perspective.Frontiers in psychology · 2020Review
- Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice.GeroScience · 2019Article
- Predictors of Source Memory Success and Failure in Older Adults.Frontiers in aging neuroscience · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Working memory abilities significantly decrease with advancing age; hence, the search for factors that may increase or mitigate this decline is critical. Several factors have been identified that influence working memory; however, their effects have been mainly assessed separately and rarely together with other factors in the same sample. We examined 120 variables to search for factors that jointly act as mediators of working memory decay across the adult life span. A sample of 1652 healthy adults was assessed in spatial and verbal working memory domains. Structural equation modeling analyses were conducted to search for potential mediators that intervened between age and working memory. Only 14 and 10 variables reliably mediated spatial and verbal working memory, respectively. Factors from several domains remained in the models, such as individual characteristics, physiological traits, consumption habits, and regular activities. These factors are sufficiently powerful to influence working memory decline when they jointly interact, as in everyday living.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.