Evidence map›Paper›PMID 29968013›Full record

ArticleIntensive care medicine2018

Premorbid functional status as a predictor of 1-year mortality and functional status in intensive care patients aged 80 years or older.

Laura Pietiläinen, Johanna Hästbacka, Minna Bäcklund, Ilkka Parviainen, Ville Pettilä, Matti Reinikainen

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Article in Intensive care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Premorbid Clinical Frailty Score and 30-day mortality among older adults in the emergency department.Journal of the American College of Emergency Physicians open · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Laura PietiläinenDepartment of Anaesthesiology, Kuopio University Hospital, P.O. Box 100, 70029, Kuopio, Finland. laura.pietilainen@kuh.fi.ORCID http://orcid.org/0000-0001-5457-9466
Johanna HästbackaDivision of Intensive Care Medicine, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Minna BäcklundDivision of Intensive Care Medicine, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ilkka ParviainenDepartment of Intensive Care, Kuopio University Hospital, Kuopio, Finland.
Ville PettiläDivision of Intensive Care Medicine, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Matti ReinikainenDepartment of Intensive Care, North Karelia Central Hospital, Joensuu, Finland.

Funding

Kuopion Yliopistollinen Sairaala EVO 5070241
6 · The paper itself

Abstract

purposeWe assessed the association between the premorbid functional status (PFS) and 1-year mortality and functional status of very old intensive care patients.

methodsUsing a nationwide quality registry, we retrieved data on patients treated in Finnish intensive care units (ICUs) during the period May 2012‒April 2013. Of 16,389 patients, 1827 (11.1%) were very old (aged 80 years or older). We defined a person with good functional status as someone independent in activities of daily living (ADL) and able to climb stairs without assistance; a person with poor functional status was defined as needing assistance for ADL or being unable to climb stairs. We adjusted for severity of illness and calculated the impact of PFS.

resultsOverall, hospital mortality was 21.3% and 1-year mortality was 38.2%. For emergency patients (73.5% of all), hospital mortality was 28% and 1-year mortality was 48%. The functional status at 1 year was comparable to the PFS in 78% of the survivors. PFS was poor for 43.3% of the patients. A poor PFS predicted an increased risk of in-hospital death, adjusted odds ratio (OR) 1.50 (95% confidence interval, 1.07-2.10), and of 1-year mortality, OR 2.18 (1.67-2.85). PFS data significantly improved the prediction of 1-year mortality.

conclusionsOf very old ICU patients, 62% were alive 1 year after ICU admission and 78% of the survivors had a functional status comparable to the premorbid situation. A poor PFS doubled the odds of death within a year. Knowledge of PFS improved the prediction of 1-year mortality.

Indexed as

Activities of Daily LivingCritical CareIntensive Care UnitsAged, 80 and overFemaleFinlandHospital MortalityHumansMalePrognosisProspective StudiesRegistriesFrailtyFunctional statusICUIntensive careMortalityVery old

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.