Evidence map›Paper›PMID 29967892›Full record

ArticleJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2017

Neutropenia and T-Wave Inversion as Toxin-Mediated Complications of a Streptococcal Infection.

Cristina Popescu, Anca Leuştean, Alina Elena Orfanu, Codruţa Georgiana Carp, Victoria Aramă

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cristina Popescu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Anca Leuştean"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Alina Elena Orfanu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Codruţa Georgiana Carp"Prof. Dr. Matei Balş" National Institute for Infectious Diseases, Bucharest, Romania.
Victoria Aramă"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
National Institute of Research and Development for Biological Sciences · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStreptococcal infection can be responsible for multiple complications, such as toxic, septic or allergic disorders. Toxin-mediated complications (TMC) can appear during the acute phase of disease and can involve any organ, causing carditis, arthritis, nephritis, hepatitis etc. CASE PRESENTATION: The case of a young woman without a history of recurrent streptococcal tonsillitis, admitted to "Matei Balş" National Institute for Infectious Diseases, Bucharest, Romania, presenting with fever, sore throat and exudative tonsillitis, is detailed. The initial test for Streptococcus pyogenes was negative. The patient had leukopenia with severe neutropenia, high values of inflammatory biomarkers and electrocardiographic (ECG) changes with inverted T waves in leads V1-4 and flattened T waves in V5-6. There were no other cardiac signs or symptoms. The patient received cefuroxime for two days. On admission, the patient was prescribed Penicillin G and dexamethasone which resulted in a rapid recovery. The leucocytes count returned to normal as did the ECG abnormalities. At the time of discharge, the antistreptolysin O titre was high.

conclusionsThe case highlights the toxin-mediated complications (TMC) of streptococcal infection which occur from the outset of the disease.

Indexed as

leukopeniastreptococcal infectiontonsillitistoxic myocarditis

Identifiers

PMID29967892
PMCPMC5769906
OpenAlexW2767228986

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.