ArticleJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2017
Clinical Features and Outcomes of
Article in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Alterations of the nasal and oral microbiota in multiple sclerosis.EBioMedicine · 2025Article
- Integrated spatial multi-omics profiling of Fusobacterium nucleatum in breast cancer unveils its role in tumour microenvironment modulation and cancer progression.Clinical and translational medicine · 2025Article
- Risk of mortality in Fusobacterium species bloodstream infection from a large Australian cohort.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- The emerging role of Fusobacteria in carcinogenesis.European journal of clinical investigation · 2024Review
- Article
- Epidemiology and Clinical Outcomes ofMedicina (Kaunas, Lithuania) · 2024Article
- Alterations in Gut Microbiota Correlate With Hematological Injuries Induced by Radiation in Beagles.International journal of microbiology · 2024Article
- Bilateral parapneumonic empyema caused byIDCases · 2024Article
- Bacterial diversity and community characteristics of the sinus and dental regions in adults with odontogenic sinusitis.BMC microbiology · 2023Article
- Article
- Article
- The role of gut microbiota in clinical complications, disease severity, and treatment response in severe alcoholic hepatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Article
- Identification of Fusobacterium nucleatum in primary and secondary endodontic infections and its association with clinical features by using two different methods.Clinical oral investigations · 2021Article
- Efficacy of the Endolysin-Based Antibacterial Gel for Treatment of Anaerobic Infection Caused byAntibiotics (Basel, Switzerland) · 2021Article
- Article
- Heat-KilledMolecules (Basel, Switzerland) · 2020Article
- Article
- Severe case of pneumonia with pleural effusion in an immunocompromised woman due toBMJ case reports · 2019Article
- Bacteraemia and multiple liver abscesses due toBMJ case reports · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough uncommon, Fusobacterium infections have a wide clinical spectrum, ranging from local pharyngeal infections to septic shock. Our aim was to characterize and analyze the clinical features and outcomes in patients with Fusobacterium infections, and determine which variables were able to predict a poor outcome.
methodsWe conducted a retrospective, hospital-based study using the computerized records of a second-level Spanish general hospital, serving a population of 155,000 inhabitants. The cohort was enrolled among patients cared for at the hospital between 2007 and 2016. Demographic, clinical data, microbiological characterization and outcomes at discharge, were analyzed.
resultsWe collected data for all 26 patients over a 10-year period (annual incidence of 1.78 per 100,000), with an incidence of bacteremia of 0.53 cases per 100,000 population per year. F. nucleatum and F. necrophorum were the most frequent isolations (53.8% and 38.5%, respectively). F. necrophorum was found to be associated with a younger population. Although we found no deaths attributable to Fusobacterium, 15 patients (57%) were found to have severe infections due to this pathogen, and 7 patients (26.9%) were admitted to the Intensive Care Unit (ICU). The only identifiable risk factor for a severe infection (sepsis, septic shock or ICU admission) was the presence of bacteremia.
conclusionsFusobacterium infections are uncommon. F. necrophorum tends to cause infection in younger individuals, while F. nucleatum has a preference for older patients. The clinical spectrum is wide, ranging from local, nonsevere infections, such as sinusitis or pharyngitis, to abscess formation and life-threatening infections.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.