Evidence map›Paper›PMID 29967880›Full record

ReviewJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2017

The Importance of Haemogram Parameters in the Diagnosis and Prognosis of Septic Patients.

Alina Elena Orfanu, Cristina Popescu, Anca Leuștean, Anca Ruxandra Negru, Cătălin Tilişcan, Victoria Aramă, Ștefan Sorin Aramă

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Observational
  10. Diagnostic Challenges in Sepsis.Current infectious disease reports · 2021
    Review
  11. Article
  12. The complete blood count to diagnose septic shock.Journal of thoracic disease · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alina Elena OrfanuNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Cristina PopescuNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Anca LeușteanNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Anca Ruxandra NegruNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Cătălin TilişcanNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Victoria AramăNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Ștefan Sorin AramăNational Institute for Infectious Diseases "Prof. Dr Matei Balș", Dr Calistrat Grozovici Street, no 1, 021105, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis represents a severe pathology that requires both rapid and precise positive and differential diagnosis to identify patients who need immediate antimicrobial therapy. Monitoring septic patients' outcome leads to prolonged hospitalisation and antibacterial therapy, often accompanied by substantial side effects, complications and a high mortality risk. Septic patients present with complex pathophysiological and immunological disorders and with a predominance of pro-inflammatory or anti-inflammatory mediators which are heterogeneous with respect to the infectious focus, the aetiology of sepsis or patients' immune status or comorbidities. Previous studies performed have analysed inflammatory biomarkers, but a test or combinations of tests that can quickly and precisely establish a diagnosis or prognosis of septic patients has yet to be discovered. Recent research has focused on re-analysing older accessible parameters found in the complete blood count to determine the sensitivity, specificity, positive and negative predictive values for the diagnosis and prognosis of sepsis. The neutrophil/lymphocyte count ratio (NLCR), mean platelet volume (MPV) and red blood cells distribution width (RDW) are haemogram indicators which have been evaluated and which are of proven use in septic patients' management.

Indexed as

mean platelet volumeneutrophil/lymphocyte count ratiored blood cells distribution widthsepsis

Identifiers

PMID29967880
PMCPMC5769899
OpenAlexW2749876740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.