ArticleBioMed research international2018
Relation of Lean Body Mass and Muscle Performance to Serum Creatinine Concentration in Hemodialysis Patients.
Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk prediction models for sarcopenia in maintenance hemodialysis patients: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Skeletal muscle atrophy in clinical and preclinical models of chronic kidney disease: A systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Pretransplant Serum Creatinine in Peritoneal Dialysis Patients Predicts Graft Outcomes.Kidney medicine · 2025Article
- The role of lean body mass in predicting mortality in hemodialysis patients across different age groups.Scientific reports · 2025Article
- Development of a Practical Screening Tool to Predict Sarcopenia in Patients on Maintenance Hemodialysis.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Psoas muscle index predicts time to rehospitalization in liver cirrhosis: An observational study.Medicine · 2022Observational
- Creatinine index as a predictive marker of sarcopenia in patients under hemodialysis.International urology and nephrology · 2022Article
- Evaluation of the Effects of Agro Pesticides Use on Liver and Kidney Function in Farmers from Buea, Cameroon.Journal of toxicology · 2020Article
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Authors and funding
4 authors.
Funding
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Abstract
introductionSerum creatinine concentration is an important uremic marker and predictor of survival in dialysis patients. This cross-sectional case-control study was made to quantitatively describe the relation between lean body mass (LBM), physical performance measures, and serum creatinine values.
methodsNinety hemodialysis patients and 106 controls were measured by bioimpedance spectroscopy, handgrip strength, sit-to-stand test, and biochemical serum tests. Univariate and multivariate general linear models were used to analyze quantitative relations.
resultsAt univariate regression LBM accounted for 13.6% variability of serum creatinine concentration. In adjusted analyses with age, height, and body mass, LBM persisted as the only significant predictor of midweek predialysis serum creatinine concentration. Physical performance measures handgrip strength and sit-to-stand performance did not improve prediction of serum creatinine. With addition of serum urea concentration and residual diuresis the predictive value of the regression model improved to account for 45% of serum creatinine variability. Each kg of LBM was associated with 7.7
conclusionBioimpedance derived LBM has a significant linear relation with predialysis serum creatinine concentrations. Hereby described quantitative relation should help clinicians to better evaluate observed creatinine concentrations of hemodialysis patients when bioimpedance derived LBM is available.
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