Evidence map›Paper›PMID 29967764›Full record

ArticleFrontiers in bioengineering and biotechnology2018

Novel Features and Considerations for ERA and Regulation of Crops Produced by Genome Editing.

Nina Duensing, Thorben Sprink, Wayne A Parrott, Maria Fedorova, Martin A Lema, Jeffrey D Wolt, Detlef Bartsch

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. 3Bs of CRISPR-Cas mediated genome editing in plants: exploring the basics, bioinformatics and biosafety landscape.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. GMOs or non-GMOs? The CRISPR Conundrum.Frontiers in plant science · 2023
    Review
  15. Review
  16. The Promising Nanovectors for Gene Delivery in Plant Genome Engineering.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Review
  19. An Outlook on Global Regulatory Landscape for Genome-Edited Crops.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Nina DuensingBundesamt für Verbraucherschutz und Lebensmittelsicherheit, Berlin, Germany.
Thorben SprinkInstitute for Biosafety in Plant Biotechnology, Julius Kuehn Institute, Quedlinburg, Germany.
Wayne A ParrottDepartment of Crop and Soil Sciences, Institute of Plant Breeding, Genetics and Genomics, University of Georgia, Athens, GA, United States.
Maria FedorovaCorteva Agriscience™, Agriculture Division of DowDuPont™, Johnston, IA, United States.
Martin A LemaBiotechnology Directorate, Ministry of Agro-Industry, Buenos Aires, Argentina.
Jeffrey D WoltDepartment of Agronomy and Crop Bioengineering Center, Iowa State University, Ames, IA, United States.
Detlef BartschBundesamt für Verbraucherschutz und Lebensmittelsicherheit, Berlin, Germany.
Federal Office of Consumer Protection and Food Safety · DECorteva (United States) · USIowa State University · USJulius Kühn-Institut · DENational University of Quilmes · ARUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome editing describes a variety of molecular biology applications enabling targeted and precise alterations of the genomes of plants, animals and microorganisms. These rapidly developing techniques are likely to revolutionize the breeding of new crop varieties. Since genome editing can lead to the development of plants that could also have come into existence naturally or by conventional breeding techniques, there are strong arguments that these cases should not be classified as genetically modified organisms (GMOs) and be regulated no differently from conventionally bred crops. If a specific regulation would be regarded necessary, the application of genome editing for crop development may challenge risk assessment and post-market monitoring. In the session "Plant genome editing-any novel features to consider for ERA and regulation?" held at the 14th ISBGMO, scientists from various disciplines as well as regulators, risk assessors and potential users of the new technologies were brought together for a knowledge-based discussion to identify knowledge gaps and analyze scenarios for the introduction of genome-edited crops into the environment. It was aimed to enable an open exchange forum on the regulatory approaches, ethical aspects and decision-making considerations.

Indexed as

CRISPR/Casenvironmental risk assessment (ERA)genome editingISBGMOISBRnew breeding techniques (NBT)regulation

Identifiers

PMID29967764
PMCPMC6016284
OpenAlexW2805892967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.