Evidence map›Paper›PMID 29967685›Full record

ReviewArrhythmia & electrophysiology review2018

Premature Ventricular Complex-induced Cardiomyopathy.

Jorge G Panizo, Sergio Barra, Greg Mellor, Patrick Heck, Sharad Agarwal

Open access · goldAbstract readReview
In one paragraph

Review in Arrhythmia & electrophysiology review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Premature ventricular contraction-induced ventricular dysfunction in children without structural heart disease: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  3. Revisiting Secondary Dilative Cardiomyopathy.International journal of molecular sciences · 2025
    Pooled it
  4. Guideline
  5. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jorge G PanizoRoyal Papworth Hospital NHS Foundation Trust, Cambridge University Health Partners Cambridge, UK.
Sergio BarraRoyal Papworth Hospital NHS Foundation Trust, Cambridge University Health Partners Cambridge, UK.
Greg MellorRoyal Papworth Hospital NHS Foundation Trust, Cambridge University Health Partners Cambridge, UK.
Patrick HeckRoyal Papworth Hospital NHS Foundation Trust, Cambridge University Health Partners Cambridge, UK.
Sharad AgarwalRoyal Papworth Hospital NHS Foundation Trust, Cambridge University Health Partners Cambridge, UK.
Cambridge University Health Partners · GBPapworth Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Premature ventricular complex-induced cardiomyopathy is a potentially reversible condition in which left ventricular dysfunction is induced by the occurrence of frequent premature ventricular complexes (PVCs). Various cellular and extracellular mechanisms and risk factors for developing cardiomyopathy in this context have been suggested but the exact pathophysiological mechanism remains unclear. The suppression of PVCs is usually indicated in symptomatic patients with frequent PVCs and also those with left ventricular dysfunction. Antiarrhythmic drugs are a useful non-invasive treatment to eliminate PVCs, but the side effect profile, including the risk of pro-arrhythmia, along with suboptimal clinical effectiveness, should be weighed against the usually more effective but not risk-free treatment with catheter ablation. The latter has progressively become first line therapy in many patients with PVC-induced cardiomyopathy and should be particularly considered in specific scenarios.

Indexed as

antiarrhythmic drug;arrhythmia;cardiomyopathy,heart failure;non-sustained ventricular tachycardiaoutflow tract;palpitations;Premature ventricular complex,radiofrequency catheter ablation;ventricular dysfunction,

Identifiers

PMID29967685
PMCPMC6020182
OpenAlexW2808796978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.