Evidence map›Paper›PMID 29967623›Full record

ArticleFrontiers in immunology2018

Transcriptome Analysis of Bronchoalveolar Lavage Fluid From Children With

Man Gao, Kuo Wang, Mingyue Yang, Fanzheng Meng, Ruihua Lu, Huadong Zhuang, Genhong Cheng, Xiaosong Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  4. Host immune dysfunction and Mycoplasma pneumoniae immune evasion: dual drivers of pathogenesis in Mycoplasma pneumoniae pneumonia.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
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  18. Immune response plays a role inFrontiers in immunology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Man GaoDepartment of Pediatrics, The First Hospital of Jilin University, Changchun, China.
Kuo WangInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Mingyue YangInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Fanzheng MengDepartment of Pediatrics, The First Hospital of Jilin University, Changchun, China.
Ruihua LuDepartment of Pediatrics, The First Hospital of Jilin University, Changchun, China.
Huadong ZhuangDepartment of Pediatrics, The First Hospital of Jilin University, Changchun, China.
Genhong ChengInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Xiaosong WangInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Jilin University · CNFirst Hospital of Jilin University · CNUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsNext-generation transcriptome sequencing was performed on the bronchoalveolar lavage fluid cells from six children with MPP and three children with foreign body aspiration as control. Some of the results had been validated by quantitative real-time PCR in an expanded group of children.

resultsResults revealed 810 differentially expressed genes in MPP group comparing to control group, of which 412 genes including

conclusionOur results suggest that NK and CD8+ T cells are over activated and proliferated in MPP children; the upregulated

Indexed as

bronchoalveolar lavage fluidCD8+ T cellschildreninterferon gammaMycoplasma pneumoniae pneumonianatural killer cells

Identifiers

PMID29967623
PMCPMC6015898
OpenAlexW2807568210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.