Evidence map›Paper›PMID 29967622›Full record

ArticleFrontiers in immunology2018

Impact of Mothers' Schistosomiasis Status During Gestation on Children's IgG Antibody Responses to Routine Vaccines 2 Years Later and Anti-Schistosome and Anti-Malarial Responses by Neonates in Western Kenya.

Bartholomew N Ondigo, Erick M O Muok, John K Oguso, Sammy M Njenga, Henry M Kanyi, Eric M Ndombi, Jeffrey W Priest, Nupur Kittur, William Evan Secor, Diana M S Karanja and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. SCORE Studies on the Impact of Drug Treatment on Morbidity due toThe American journal of tropical medicine and hygiene · 2020
    Pooled it
  3. Fine-scale heterogeneity inProceedings of the National Academy of Sciences of the United States of America · 2020
    Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Schistosomiasis Seroprevalence among Children Aged 0-14 Years in Nigeria, 2018.The American journal of tropical medicine and hygiene · 2024
    Article
  9. The Global Prevalence ofTropical medicine and infectious disease · 2022
    Review
  10. Altered Offspring Immunity in Maternal Parasitic Infections.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Bartholomew N OndigoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
Erick M O MuokCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
John K OgusoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
Sammy M NjengaEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Henry M KanyiEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Eric M NdombiCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
Jeffrey W PriestDivision of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Nupur KitturCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
William Evan SecorDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Diana M S KaranjaCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
Daniel G ColleyCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Kenya Medical Research Institute · KECenters for Disease Control and Prevention · USUniversity of Georgia · US

Funding

Determinants of resistance in human schistosomiasisR01AI053695 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI COLLEY, DANIEL G · 2003 to 2014
$5.2M
NIAID NIH HHS R01 AI053695
6 · The paper itself

Abstract

The potential consequences of parasitic infections on a person's immune responsiveness to unrelated antigens are often conjectured upon in relationship to allergic responses and autoimmune diseases. These considerations sometimes extend to whether parasitic infection of pregnant women can influence the outcomes of responses by their offspring to the immunizations administered during national Expanded Programs of Immunization. To provide additional data to these discussions, we have enrolled 99 close-to-term pregnant women in western Kenya and determined their

Indexed as

antibody responsesdiphtheriamalariameaslesschistosomiasistetanusvaccines

Identifiers

PMID29967622
PMCPMC6015899
OpenAlexW2807275960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.