Evidence map›Paper›PMID 29967590›Full record

ArticleFrontiers in endocrinology2018

Brain-Derived Steroids, Behavior and Endocrine Conflicts Across Life History Stages in Birds: A Perspective.

John C Wingfield, Douglas W Wacker, George E Bentley, Kazuyoshi Tsutsui

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

John C WingfieldDepartment of Neurobiology Physiology and Behavior, University of California, Davis, Davis, CA, United States.
Douglas W WackerDivision of Biological Sciences, School of STEM, University of Washington Bothell, Bothell, WA, United States.
George E BentleyDepartment of Integrative Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States.
Kazuyoshi TsutsuiDepartment of Biology, Waseda University, Shinjuku, Japan.
University of California, Berkeley · USUniversity of California, Davis · USUniversity of Washington Bothell · USWaseda University · JP

Funding

NEURAL STEROIDOGENIC ENZYMES AND BRAIN FUNCTIONR01MH061994 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SCHLINGER, BARNETT ALAN · 2000 to 2014
$4.1M
NIMH NIH HHS R01 MH061994
6 · The paper itself

Abstract

Biological steroids were traditionally thought to be synthesized exclusively by the adrenal glands and gonads. Recent decades have seen the discovery of neurosteroid production that acts locally within the central nervous system to affect physiology and behavior. These actions include, for example, regulation of aggressive behavior, such as territoriality, and locomotor movement associated with migration. Important questions then arose as to how and why neurosteroid production evolved and why similar steroids of peripheral origin do not always fulfill these central roles? Investigations of free-living vertebrates suggest that synthesis and action of bioactive steroids within the brain may have evolved to regulate expression of specific behavior in different life history stages. Synthesis and secretion of these hormones from peripheral glands is broadcast throughout the organism

Indexed as

7α-hydroxypregnenolonearomatasedehydropepiandrosteronelife history stageslocomotor activityneurosteroidterritorial aggression

Identifiers

PMID29967590
PMCPMC6015890
OpenAlexW2802779613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.