Evidence map›Paper›PMID 29967572›Full record

ArticleContrast media & molecular imaging2018

Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the

Marco F Taddio, Linjing Mu, Claudia Keller, Roger Schibli, Stefanie D Krämer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Performance and Sensitivity of [Molecular pharmaceutics · 2024
    Article
  2. Article
  3. Use of imaging to assess the activity of hepatic transporters.Expert opinion on drug metabolism & toxicology · 2020
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco F TaddioRadiopharmaceutical Science and Biopharmacy, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-2477-5575
Linjing MuDepartment of Nuclear Medicine, University Hospital Zurich, Switzerland.
Claudia KellerRadiopharmaceutical Science and Biopharmacy, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.
Roger SchibliRadiopharmaceutical Science and Biopharmacy, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-1537-3833
Stefanie D KrämerRadiopharmaceutical Science and Biopharmacy, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-0426-4340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physiologically based pharmacokinetic modelling (PBPK) is a powerful tool to predict

Indexed as

AnimalsCarbon RadioisotopesCarrier ProteinsCyclosporineHepatobiliary EliminationHumansMetabolic Clearance RateMiceModels, TheoreticalPharmacokineticsPositron-Emission TomographyRadiopharmaceuticalsCarbon RadioisotopesCarrier ProteinsCyclosporineRadiopharmaceuticals

Identifiers

PMID29967572
PMCPMC6008768

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.