ArticlePediatric research2018
Maternal and infant vitamin B12 status during infancy predict linear growth at 5 years.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Vitamin B12 and Folate Status in Pregnant Females and Their Infants in Norway: Secondary Analysis from the Mommy's Food Study.The Journal of nutrition · 2023Trial
- Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal.Journal of nutritional science · 2021Trial
- Effects of vitamin B12 supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial.PLoS medicine · 2020Trial
- Systems biology insights into the molecular drivers of childhood stunting and implications for intervention.Frontiers in nutrition · 2026Review
- Dietary pattern and nutritional assessment in a cohort of mothers identified by neonatal screening for cobalamin deficiency in offspring: an Italian single center experience.Frontiers in nutrition · 2025Article
- Review
- Breastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional study.Journal of nutritional science · 2024Article
- The gut microbiome and early-life growth in a population with high prevalence of stunting.Nature communications · 2023Article
- Infant age at egg introduction and malnutrition-related child growth in the United States.Maternal & child nutrition · 2022Article
- Dietary Intake and Biomarkers of Folate and Cobalamin Status in Norwegian Preschool Children: The FINS-KIDS Study.The Journal of nutrition · 2020Article
- Vitamin B12 Intake From Animal Foods, Biomarkers, and Health Aspects.Frontiers in nutrition · 2019Review
- Maternal and infant vitamin B12 status and development.Pediatric research · 2018Article
- Policy threats to maternal and child nutrition: putting the unborn child at a lifelong disadvantage.Pediatric research · 2018Article
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Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany children worldwide have poor vitamin B12 status. The objective of this study was to estimate association between maternal and infant vitamin B12 status and long-term growth.
methodsWe randomly selected 500 Nepali mother-infant pairs and measured maternal intake and infant and maternal vitamin B12 status using plasma cobalamin, total plasma homocysteine, and methylmalonic acid concentrations. We revisited available children when they were 5 years old and measured growth. The associations between intake and maternal and infant markers of vitamin B12 and growth were estimated in multiple linear regression models adjusting for relevant confounders (n = 331).
resultsMaternal vitamin B12 intake and status and vitamin B12 status in infancy predicted linear growth at 5 years of age, but not during infancy. Each microgram increase in the vitamin B12 intake of the mother during infancy was associated with an increase in height of 0.4 (0.2, 0.6) height-for-age z-scores and 1.7 (0.7, 2.7) cm around the child's fifth birthday.
conclusionVitamin B12 status and intake in early life is an important determinant for linear growth at school age. Our findings should be verified in randomized, placebo controlled trials before translated into public health recommendations.
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