Evidence map›Paper›PMID 29967325›Full record

Trial reportScientific reports2018

Risk stratifiers for arrhythmic and non-arrhythmic mortality after acute myocardial infarction.

Alfonso M Gañán-Calvo, Katerina Hnatkova, Álvaro Romero-Calvo, Juan Fajardo-López, Marek Malik

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alfonso M Gañán-CalvoUniversidad de Sevilla, Depto. de Ingeniería Aeroespacial y Mecánica de Fluidos, Sevilla, E-41092, Spain. amgc@us.es.ORCID 0000-0002-7552-6184
Katerina HnatkovaImperial College, National Heart and Lung Institute, London, SW3 6LY, United Kingdom.
Álvaro Romero-CalvoLynzos SL, Engineering Department, Sevilla, E-41018, Spain.ORCID 0000-0003-3369-8460
Juan Fajardo-LópezClínica HLA Santa Isabel, Intensive Care Unit, Sevilla, E-41018, Spain.
Marek MalikImperial College, National Heart and Lung Institute, London, SW3 6LY, United Kingdom.

Funding

British Heart Foundation NH/16/2/32499
6 · The paper itself

Abstract

The effective discrimination between patients at risk of Arrhythmic Mortality (AM) and Non-Arrhythmic Mortality (NAM) constitutes one of the important unmet clinical needs. Successful risk assessment based on Electrocardiography (ECG) records is greatly improved by the combination of different indices reflecting not only the pathological substrate but also the autonomic regulation of cardiac electrophysiology. This study assesses the cardiac risk stratification capacity of two new Heart Rate Variability (HRV) parameters, Breath Concurrence 6 (BC6) -sinusoidal RR variability of 6 heart beats per breath cycle- and Primary Ectopia (PE) -presence of early ventricular contractions of any etiology- together with the Deceleration Capacity (DC). While BC6 characterizes the response to physiological and pathophysiological stimuli, PE qualifies autonomic cardiac electrophysiology. The analysis of the European Myocardial Infarct Amiodarone Trial (EMIAT) database indicates that BC6 is related with the risk of Arrhythmic Mortality (AM) and PE with the risk of Non-Arrhythmic Mortality. BC6 is the only single parameter that significantly discriminates between AM and NAM. While the combination of BC6 and DC contributes to the identification of AM risk, PE together with DC improves the prediction of NAM in patients with severe ischemic heart disease.

Indexed as

Arrhythmias, CardiacElectrocardiographyFollow-Up StudiesHeart RateHumansKaplan-Meier EstimateMyocardial InfarctionRisk FactorsSignal Processing, Computer-AssistedVentricular Function, Left

Identifiers

PMID29967325
PMCPMC6028459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.