ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018
Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.
Open access · greenAbstract read
In one paragraph
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2024 for the Clinical Practice of Inflammatory Bowel Disease-Associated Intestinal Neoplasia (English Version).Journal of the anus, rectum and colon · 2026Review
- Machine learning‑based radiomics models accurately predict Crohn's disease‑related anorectal cancer.Oncology letters · 2024Article
- Dissecting the Mechanisms of Intestinal Immune Homeostasis by Analyzing T-Cell Immune Response in Crohn's Disease and Colorectal Cancer.Current gene therapy · 2024Article
- Tumor cell malignancy: A complex trait built through reciprocal interactions between tumors and tissue-body system.iScience · 2022Review
- Molecular Network of Colorectal Cancer and Current Therapeutic Options.Frontiers in oncology · 2022Review
- Prognostic relevance and putative histogenetic role of cytokeratin 7 and MUC5AC expression in Crohn's disease-associated small bowel carcinoma.Virchows Archiv : an international journal of pathology · 2021Article
- Article
- Molecular characterization of ulcerative colitis-associated colorectal carcinomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Article
- The genomic landscape of carcinomas with mucinous differentiation.Scientific reports · 2021Article
- Landscape of cell heterogeneity and evolutionary trajectory in ulcerative colitis-associated colon cancer revealed by single-cell RNA sequencing.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021Article
- Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system.Journal of cancer research and clinical oncology · 2021Article
- High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients.The American journal of pathology · 2020Article
- Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020Article
- Non-conventional mucosal lesions (serrated epithelial change, villous hypermucinous change) are frequent in patients with inflammatory bowel disease-results of molecular and immunohistochemical single institutional study.Virchows Archiv : an international journal of pathology · 2020Article
- Management of Perianal Fistulas in Crohn's Disease.Visceral medicine · 2019Review
- [Colorectal tumor evolution in inflammatory bowel disease : Dynamics of genomic alterations and potential molecular markers to predict malignant progression].Der Pathologe · 2019Review
- Transcriptome Sequencing Investigated the Tumor-Related Factors Changes AfterFrontiers in microbiology · 2019Article
- [Crohn's disease-associated colorectal carcinogenesis : TP53 mutations and copy number gains of chromosome arm 5p as (early) markers of tumor progression].Der Pathologe · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Daniela HirschInstitute of Pathology, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
Darawalee WangsaCancer Genomics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Yuelin J ZhuMolecular Genetics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Yue HuCancer Genomics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Daniel C EdelmanMolecular Genetics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Paul S MeltzerMolecular Genetics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Kerstin Heselmeyer-HaddadCancer Genomics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Claudia OttDepartment of Internal Medicine I, University Medical Center Regensburg, Regensburg, Germany.
Peter KienleDepartment of Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
Christian GalataDepartment of Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
Karoline Horisberger *Department of Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
Thomas Ried *Cancer Genomics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland. timo.gaiser@umm.de riedt@mail.nih.gov.
Timo Gaiser *Institute of Pathology, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany. timo.gaiser@umm.de riedt@mail.nih.gov.
Heidelberg University · DECenter for Cancer Research · USCancer Genetics (United States) · USUniversity Hospital Regensburg · DE
Funding
Molecular Profiling of Clinical SpecimensZICBC011040 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI EDELMAN, DANIEL · 2009 to 2020
$25.5MCancer Genomics Technology DevelopmentZIABC011091 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MELTZER, PAUL S. · 2009 to 2025
$16.9MTechnical Development of Molecular Profiling TechnologiesZICBC011041 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI EDELMAN, DANIEL · 2009 to 2020
$3.7MIdentification and functional characterization of colorectal cancer genesZ01BC010833 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RIED, THOMAS · 2007 to 2008
$1.5MCancer Genomics Technology DevelopmentZ01BC011091 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MELTZER, PAUL S. · 2008 to 2008
$790kIntramural NIH HHS Z01 BC010833Intramural NIH HHS Z01 BC011091Intramural NIH HHS ZIC BC011041
Abstract
PubMed holds no abstract for this paper.
Indexed as
Genetic VariationGenomicsAdultBiomarkersCell Transformation, NeoplasticColorectal NeoplasmsComparative Genomic HybridizationCrohn DiseaseDisease ProgressionFemaleHumansImmunohistochemistryIn Situ Hybridization, FluorescenceIntestinal MucosaMaleMicrosatellite RepeatsBiomarkers
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.