Evidence map›Paper›PMID 29967142›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Human impact on the diversity and virulence of the ubiquitous zoonotic parasite

E Keats Shwab, Pooja Saraf, Xing-Quan Zhu, Dong-Hui Zhou, Brent M McFerrin, Daniel Ajzenberg, Gereon Schares, Kenneth Hammond-Aryee, Paul van Helden, Steven A Higgins and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Evolution ofJournal of parasitology research · 2026
    Review
  6. Article
  7. Review
  8. Population genetic structure of zoonoticScience in One Health · 2026
    Article
  9. Isolation, genotyping and phenotypingFood and waterborne parasitology · 2025
    Review
  10. International journal for parasitology. Parasites and wildlife · 2025
    Article
  11. [Seroprevalence ofMedecine tropicale et sante internationale · 2025
    Article
  12. Novel drug candidates targetingFrontiers in pharmacology · 2025
    Article
  13. Transboundary and emerging diseases · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Human T-cell activation withLife science alliance · 2024
    Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

E Keats ShwabDepartment of Microbiology, The University of Tennessee, Knoxville, TN 37996.
Pooja SarafDepartment of Microbiology, The University of Tennessee, Knoxville, TN 37996.
Xing-Quan ZhuState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046 Gansu Province, People's Republic of China.
Dong-Hui ZhouState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046 Gansu Province, People's Republic of China.
Brent M McFerrinDepartment of Mechanical, Aerospace, and Biomedical Engineering, The University of Tennessee, Knoxville, TN 37996.
Daniel AjzenbergInstitut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1094, Université de Limoges, F-87000 Limoges, France.
Gereon ScharesInstitute of Epidemiology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.
Kenneth Hammond-AryeeDepartment of Science and Technology, National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 8000, South Africa.
Paul van HeldenDepartment of Science and Technology, National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 8000, South Africa.
Steven A HigginsDepartment of Microbiology, The University of Tennessee, Knoxville, TN 37996.
Richard W GerholdDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996.
Benjamin M RosenthalAgricultural Research Service, Animal Parasitic Diseases Laboratory, US Department of Agriculture, Beltsville, MD 20705.ORCID 0000-0002-0224-3773
Xiaopeng ZhaoDepartment of Mechanical, Aerospace, and Biomedical Engineering, The University of Tennessee, Knoxville, TN 37996.
Jitender P DubeyAgricultural Research Service, Animal Parasitic Diseases Laboratory, US Department of Agriculture, Beltsville, MD 20705 jitender.dubey@ars.usda.gov csu1@utk.edu.
Chunlei SuDepartment of Microbiology, The University of Tennessee, Knoxville, TN 37996; jitender.dubey@ars.usda.gov csu1@utk.edu.ORCID 0000-0001-8392-7108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A majority of emerging infectious diseases in humans are zoonoses. Understanding factors that influence the emergence and transmission of zoonoses is pivotal for their prevention and control.

Indexed as

AnimalsCatsHuman MigrationHumansMiceSouth AmericaToxoplasmaToxoplasmosisZoonosesevolutionmathematical modelingpopulation geneticsToxoplasma gondiivirulence

Identifiers

PMID29967142
PMCPMC6055184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.