Evidence map›Paper›PMID 29967092›Full record

ArticleInfection and immunity2018

The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.

Louis-Philippe Leroux, Julie Lorent, Tyson E Graber, Visnu Chaparro, Laia Masvidal, Maria Aguirre, Bruno D Fonseca, Léon C van Kempen, Tommy Alain, Ola Larsson and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Trem2 negatively regulates the MTOR-PKCα axis to protect againstFrontiers in cellular and infection microbiology · 2026
    Article
  7. Infection and immunity · 2024
    Article
  8. Molecular diagnosis of human toxoplasmosis: the state of the art.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  9. mBio · 2023
    Article
  10. Article
  11. Ribosome Specialization in Protozoa Parasites.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Editorial: Early Events During Host Cell-Pathogen Interaction.Frontiers in cellular and infection microbiology · 2021
    Article
  18. Article
  19. Review
  20. Mechanisms of Effector-Mediated Immunity Revealed by the Accidental Human PathogenFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Louis-Philippe LerouxInstitut National de la Recherche Scientifique-Institut Armand Frappier, Laval, Quebec, Canada.ORCID https://orcid.org/0000-0002-9736-1827
Julie Lorent *Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
Tyson E Graber *Children's Hospital of Eastern Ontario Research Institute, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
Visnu ChaparroInstitut National de la Recherche Scientifique-Institut Armand Frappier, Laval, Quebec, Canada.
Laia MasvidalDepartment of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
Maria AguirreLady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Bruno D FonsecaChildren's Hospital of Eastern Ontario Research Institute, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
Léon C van KempenLady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Tommy AlainChildren's Hospital of Eastern Ontario Research Institute, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
Ola LarssonDepartment of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
Maritza JaramilloInstitut National de la Recherche Scientifique-Institut Armand Frappier, Laval, Quebec, Canada maritza.jaramillo@iaf.inrs.ca.ORCID https://orcid.org/0000-0002-1910-5684
Institut National de la Recherche Scientifique · CAScience for Life Laboratory · SEUniversity of Ottawa · CAJewish General Hospital · CAUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intracellular parasite

Indexed as

Host-Parasite InteractionsAnimalsCells, CulturedMacrophagesMiceMice, Inbred C57BLMice, KnockoutMitochondrial ProteinsProtein BiosynthesisProtozoan ProteinsRNA 5' Terminal Oligopyrimidine SequenceSignal TransductionTOR Serine-Threonine KinasesToxoplasmaMitochondrial ProteinsmTOR protein, mouseProtozoan ProteinsTOR Serine-Threonine Kinaseshost-pathogen interactionsmacrophagesmTORToxoplasma gondiitranslational control

Identifiers

PMID29967092
PMCPMC6105892
OpenAlexW2811406123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.