Evidence map›Paper›PMID 29967075›Full record

ArticleCancer discovery2018

Macropinocytosis Fuels Prostate Cancer.

Cosimo Commisso, Jayanta Debnath

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer discovery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Revealing macropinocytosis using nanoparticles.Molecular aspects of medicine · 2022
    Review
  7. Functional Diversity of Macropinocytosis.Sub-cellular biochemistry · 2022
    Article
  8. Review
  9. Mechanisms and functions of endocytosis in T cells.Cell communication and signaling : CCS · 2021
    Review
  10. Macropinocytosis: mechanism and targeted therapy in cancers.American journal of cancer research · 2021
    Review
  11. The pervasiveness of macropinocytosis in oncological malignancies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
  12. Prostate Cancer Energetics and Biosynthesis.Advances in experimental medicine and biology · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Cosimo CommissoTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California. jayanta.debnath@ucsf.edu ccommisso@sbpdiscovery.org.
Jayanta DebnathDepartment of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. jayanta.debnath@ucsf.edu ccommisso@sbpdiscovery.org.

Funding

Regulation of Nutrient Stress-Induced Macropinocytosis in Pancreatic Ductal AdenocarcinomaR01CA207189 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI COMMISSO, COSIMO · 2016 to 2025
$4.7M
NCI NIH HHS R01 CA207189
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NutrientsProstatic NeoplasmsAMP-Activated Protein KinasesHumansMalePTEN PhosphohydrolaseAMP-Activated Protein KinasesNutrientsPTEN PhosphohydrolasePTEN protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.