Evidence map›Paper›PMID 29967030›Full record

ArticleThe EMBO journal2018

RIM-binding proteins recruit BK-channels to presynaptic release sites adjacent to voltage-gated Ca

Alessandra Sclip, Claudio Acuna, Fujun Luo, Thomas C Südhof

Abstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Evaluation of fourChannels (Austin, Tex.) · 2024
    Article
  2. Article
  3. Calcium Channels and Calcium-Binding Proteins.International journal of molecular sciences · 2023
    Article
  4. CaInternational journal of molecular sciences · 2023
    Review
  5. Regulation of Neurotransmitter Release by KAdvances in neurobiology · 2023
    Article
  6. Study of the binding of ΔFN3.1 fragments of theMicrobiome research reports · 2023
    Article
  7. RIM-Binding Protein 2 Organizes CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Neurexins cluster CaThe EMBO journal · 2020
    Article
  12. Subcellular control of membrane excitability in the axon.Current opinion in neurobiology · 2019
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandra SclipDepartment of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA asclip@stanford.edu tcs1@stanford.edu.ORCID 0000-0002-9313-4176
Claudio AcunaDepartment of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
Fujun LuoDepartment of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
Thomas C SüdhofDepartment of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA asclip@stanford.edu tcs1@stanford.edu.

Funding

Role of synaptotagmins and neurexin ligands in homeostatic synaptic plasticityP50MH086403 · NIMH · STANFORD UNIVERSITY · PI DEISSEROTH, KARL A. · 2009 to 2019
$18.4M
FUNCTION OF NEUREXINSR37MH052804 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI SUDHOF, THOMAS C. · 2000 to 2019
$9.3M
NIMH NIH HHS P50 MH086403NIMH NIH HHS R37 MH052804
6 · The paper itself

Abstract

The active zone of presynaptic nerve terminals organizes the neurotransmitter release machinery, thereby enabling fast Ca

Indexed as

AnimalsCalciumCalcium ChannelsLarge-Conductance Calcium-Activated Potassium ChannelsMicePresynaptic Terminalssrc Homology DomainsSynaptic VesiclesCalciumCalcium ChannelsLarge-Conductance Calcium-Activated Potassium Channelsactive zoneBK‐channelsnano‐domain couplingneurotransmitter releasevoltage‐gated calcium channels

Identifiers

PMID29967030
PMCPMC6092624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.