Evidence map›Paper›PMID 29966346›Full record

ArticleNanomaterials (Basel, Switzerland)2018

The Effect of Polymer Microstructure on Encapsulation Efficiency and Release Kinetics of Citropin 1.1 from the Poly(ε-caprolactone) Microparticles.

Urszula Piotrowska, Ewa Oledzka, Wojciech Kamysz, Sławomir Białek, Marcin Sobczak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Susceptibility of microbial cells to the modified PIPJournal of nanobiotechnology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Urszula PiotrowskaDepartment of Biomaterials Chemistry, Chair of Analytical Chemistry and Biomaterials, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1 St., 02-097 Warsaw, Poland. upiotrowska@wum.edu.pl.ORCID 0000-0002-2418-9528
Ewa OledzkaDepartment of Biomaterials Chemistry, Chair of Analytical Chemistry and Biomaterials, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1 St., 02-097 Warsaw, Poland. eoledzka@wum.edu.pl.
Wojciech KamyszDepartment of Inorganic Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Gdansk, Al. Gen. J. Hallera 107 St., 80-416 Gdansk, Poland. wojciech.kamysz@gumed.edu.pl.
Sławomir BiałekDepartment of Biochemistry and Clinical Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1 St., 02-097 Warsaw, Poland. slawomir.bialek@wum.edu.pl.
Marcin SobczakDepartment of Biomaterials Chemistry, Chair of Analytical Chemistry and Biomaterials, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1 St., 02-097 Warsaw, Poland. marcin.sobczak@wp.pl.
Medical University of Warsaw · PLGdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cationic antimicrobial peptides represent a promising therapeutic option against multidrug-resistant bacteria for the treatment of local infections. However, due to their low stability and potential toxicity, there are limited possibilities for their application in clinical practice. In this study, different poly(ε-caprolactone) (PCL) microparticles (MPs) loaded with citropin 1.1 (CIT) were investigated in order to demonstrate the effect of the polymer microstructure on the encapsulation efficiency (

Indexed as

antimicrobial peptidesdrug releasehemotoxicitymicroparticlespoly(ε-caprolactone)

Identifiers

PMID29966346
PMCPMC6071209
OpenAlexW2810632947

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.