Evidence map›Paper›PMID 29966306›Full record

ArticleInternational journal of molecular sciences2018

Regulation of Expression of CEBP Genes by Variably Expressed Vitamin D Receptor and Retinoic Acid Receptor α in Human Acute Myeloid Leukemia Cell Lines.

Aleksandra Marchwicka, Ewa Marcinkowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Targeting WNK1 Releases Differentiation Block in Acute Myeloid Leukemia.bioRxiv : the preprint server for biology · 2026
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  19. Deficiency of RARα Suppresses DecidualizationFrontiers in endocrinology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aleksandra MarchwickaDepartment of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383 Wroclaw, Poland. alexandramarchwicka@interia.pl.
Ewa MarcinkowskaDepartment of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383 Wroclaw, Poland. ema@cs.uni.wroc.pl.ORCID 0000-0002-6808-5464
University of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All-trans-retinoic acid (ATRA) and 1α,25-dihydroxyvitamin D (1,25D) are potent inducers of differentiation of myeloid leukemia cells. During myeloid differentiation specific transcription factors are expressed at crucial developmental stages. However, precise mechanism controlling the diversification of myeloid progenitors is largely unknown, CCAAT/enhancer-binding protein (C/EBP) transcription factors have been characterized as key regulators of the development and function of the myeloid system. Past data point at functional redundancy among C/EBP family members during myeloid differentiation. In this study, we show that in acute myeloid leukemia (AML) cells, high expression of vitamin D receptor gene (

Indexed as

Blotting, WesternCCAAT-Enhancer-Binding Protein-betaCCAAT-Enhancer-Binding Protein-deltaFlow CytometryGene SilencingGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)HL-60 CellsHumansLeukemia, Myeloid, AcuteReceptors, CalcitriolRetinoic Acid Receptor alphaCCAAT-Enhancer-Binding Protein-betaCCAAT-Enhancer-Binding Protein-deltaCEBPB protein, humanCEBPD protein, humanGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)RARA protein, humanReceptors, CalcitriolRetinoic Acid Receptor alphaVDR protein, humanacute myeloid leukemiaCCAAT-enhancer-binding proteinsCEBP genesdifferentiationnuclear receptorsretinoic acid receptor αvitamin D receptor

Identifiers

PMID29966306
PMCPMC6073189
OpenAlexW2810223515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.