Evidence map›Paper›PMID 29966003›Full record

ArticlePloS one2018

Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70.

Matthew K Gilbert, Brian M Mack, Geromy G Moore, Darlene L Downey, Matthew D Lebar, Vinita Joardar, Liliana Losada, JiuJiang Yu, William C Nierman, Deepak Bhatnagar

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Climate-Driven Regulatory Plasticity Reshapes Mycotoxin Risk and Control in Food Systems.Comprehensive reviews in food science and food safety · 2026
    Review
  2. Article
  3. Distinction BetweenJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Comparative Genome Analysis of Japanese Field-IsolatedJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Genetic Diversity of Human Fungal Pathogens.Current clinical microbiology reports · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Two NewG3 (Bethesda, Md.) · 2020
    Article
  13. Fungal evolution: cellular, genomic and metabolic complexity.Biological reviews of the Cambridge Philosophical Society · 2020
    Article
  14. Review
  15. Article
  16. Fatal Rhinofacial Mycosis Due toFrontiers in microbiology · 2020
    Article
  17. Journal of fungi (Basel, Switzerland) · 2019
    Article
  18. Article
  19. TheFrontiers in microbiology · 2019
    Review
  20. Frontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew K GilbertFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.ORCID 0000-0002-8416-0217
Brian M MackFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.
Geromy G MooreFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.
Darlene L DowneyFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.
Matthew D LebarFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.
Vinita JoardarThe J. Craig Venter Institute, Rockville, Maryland, United States of America.
Liliana LosadaThe J. Craig Venter Institute, Rockville, Maryland, United States of America.
JiuJiang YuFood Quality Laboratory, USDA, Beltsville, Maryland, United States of America.
William C NiermanThe J. Craig Venter Institute, Rockville, Maryland, United States of America.
Deepak BhatnagarFood and Feed Safety Unit, USDA, New Orleans, Louisiana, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus flavus is a saprophytic fungus that infects corn, peanuts, tree nuts and other agriculturally important crops. Once the crop is infected the fungus has the potential to secrete one or more mycotoxins, the most carcinogenic of which is aflatoxin. Aflatoxin contaminated crops are deemed unfit for human or animal consumption, which results in both food and economic losses. Within A. flavus, two morphotypes exist: the S strains (small sclerotia) and L strains (large sclerotia). Significant morphological and physiological differences exist between the two morphotypes. For example, the S-morphotypes produces sclerotia that are smaller (< 400 μm), greater in quantity, and contain higher concentrations of aflatoxin than the L-morphotypes (>400 μm). The morphotypes also differ in pigmentation, pH homeostasis in culture and the number of spores produced. Here we report the first full genome sequence of an A. flavus S morphotype, strain AF70. We provide a comprehensive comparison of the A. flavus S-morphotype genome sequence with a previously sequenced genome of an L-morphotype strain (NRRL 3357), including an in-depth analysis of secondary metabolic clusters and the identification SNPs within their aflatoxin gene clusters.

Indexed as

AflatoxinsArachisAspergillus flavusCrops, AgriculturalGenome, FungalNutsPlant DiseasesSpores, FungalZea maysAflatoxins

Identifiers

PMID29966003
PMCPMC6028093

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.