Evidence map›Paper›PMID 29965971›Full record

ArticlePloS one2018

The transverse four-chamber view for the assessment of atrial tissue deformation in the fetus.

Johannes Steinhard, Andreas Entenmann, Elise van der Valk, Ralf Schmitz, Jörg Heinig, Kai Thorsten Laser, Miriam Michel

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Johannes SteinhardCenter of Pediatric Cardiology and Congenital Heart Disease, Heart- and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Ruhr University Bochum, Bochum, Germany.
Andreas EntenmannDepartment of Pediatrics (Pediatrics I), Innsbruck Medical University, Innsbruck, Austria.
Elise van der ValkDepartment of Obstetrics and Gynecology, St. Franziskus Hospital, Münster, Germany.
Ralf SchmitzPrenatal Medicine, Department of Obstetrics and Gynaecology, University of Münster, Münster, Germany.
Jörg HeinigPrenatal Medicine, Department of Obstetrics and Gynaecology, University of Münster, Münster, Germany.
Kai Thorsten LaserCenter of Pediatric Cardiology and Congenital Heart Disease, Heart- and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Ruhr University Bochum, Bochum, Germany.
Miriam MichelCenter of Pediatric Cardiology and Congenital Heart Disease, Heart- and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0002-3626-3270
Heart and Diabetes Center North Rhine-Westphalia · DEInnsbruck Medical University · ATUniversity of Münster · DESt. Franziskus Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine if atrial tissue deformation (peak strain, PS) and time to peak strain (TTPS) can be assessed in the fetus, with identification of best echocardiographic plane. MATERIALS AND

methodsPulsed-wave tissue Doppler study of a longitudinal and a transverse four-chamber view (FCV) in each of 20 healthy fetuses. Determination of PS and TTPS in regions of interest (ROI), viz., lateral walls of the right and left atria (RA, LA); comparison of values depending on section plane, with results-based discussion of the physiology of fetal atrial deformation and of possible clinical uses.

resultsPS and TTPS could be determined on transverse FCV in 91% of subjects and in 61% on longitudinal FCV. Transverse PS and TTPS were significantly higher than longitudinal (p = 0.0001). Transverse PS was significantly higher in RA than in LA (26.9% vs. 17.3%, p = 0.034), and transverse TTPS was significantly shorter in RA than in LA (p = 0.034).

conclusionAtrial radial PS and TTPS determinations are possible in the fetus. The transverse FCV is best suited for these. The highest PS values and shortest TTPS values are found in ROI representing the RA. Our findings may contribute to detailed intrauterine assessment of atrial and ventricular myocardial function.

Indexed as

Atrial Function, LeftEchocardiographyFetal HeartHeart AtriaHeart Function TestsHumans

Identifiers

PMID29965971
PMCPMC6028085
OpenAlexW2811367535

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.