Evidence map›Paper›PMID 29965856›Full record

ReviewCurrent opinion in rheumatology2018

The diagnostic work-up of cancer-associated myositis.

Albert Selva-O'Callaghan, Xavier Martinez-Gómez, Ernesto Trallero-Araguás, Iago Pinal-Fernández

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Malignancy in Idiopathic Inflammatory Myopathies: Recent Insights.Clinical reviews in allergy & immunology · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Dermatomyositis autoantibodies: how can we maximize utility?Annals of translational medicine · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. PET Scan: Nuclear Medicine Imaging in Myositis.Current rheumatology reports · 2019
    Review
  18. Article
  19. Article
  20. Dermatomyositis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Albert Selva-O'CallaghanSystemic Autoimmune Diseases Unit, Medicine Department.
Xavier Martinez-GómezPreventive Medicine and Epidemiology, Vall d'Hebron General Hospital, Universitat Autònoma de Barcelona.
Ernesto Trallero-AraguásRheumatology Unit, Vall d'Hebron General Hospital, Barcelona, Spain.
Iago Pinal-FernándezMuscle Diseases Unit, NIAMS, National Institutes of Health, Bethesda, Maryland, USA.
Adaptimmune (United Kingdom) · GBNational Institute of Arthritis and Musculoskeletal and Skin Diseases · USUniversitat Autònoma de Barcelona · ESVall d'Hebron Hospital Universitari · ES

Funding

Intramural NIH HHS Z99 AR999999
6 · The paper itself

Abstract

purpose of reviewDespite the well-recognized association between malignancy and myositis, definite data indicating the best strategy for diagnosing cancer in myositis patients is lacking. In this article, we review the data on cancer screening in patients with myositis, and propose an algorithm for this purpose based on recently published data. RECENT

findingsEvidence has recently emerged supporting blind screening in patients with certain myositis phenotypes. In addition to the clinical examination, imaging techniques such as PET/computed tomography scanning and whole-body MRI, and determination of the autoantibody profile beyond anti-TIF1γ antibody, the well known cancer biomarker in dermatomyositis, will help the clinician face this complex clinical situation. Molecules related to the checkpoint inhibitor pathway, specifically soluble programmed death 1, may also have a role in the diagnostic work-up of cancer in myositis. In the future, blood tests analysing circulating DNA will certainly help in detecting patients with cancer-associated myositis (CAM). SUMMARY: A step forward has been achieved in the pathway to establish optimal cancer screening for myositis patients. International consensus guidelines for an effective diagnostic work-up of CAM are in progress and will be of paramount importance to improving the outcome in these patients.

Indexed as

AutoantibodiesEarly Detection of CancerHumansMuscle, SkeletalMyositisNeoplasmsTomography, X-Ray ComputedAutoantibodies

Identifiers

PMID29965856
PMCPMC11611047
OpenAlexW2811473109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.