Evidence map›Paper›PMID 29965724›Full record

ArticleACS applied materials & interfaces2018

In Vivo Tracking and

Christakis Constantinides, Pooja Basnett, Barbara Lukasiewicz, Ricardo Carnicer, Edyta Swider, Qasim A Majid, Mangala Srinivas, Carolyn A Carr, Ipsita Roy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Living Nanofiber-Enabled Cardiac Patches for Myocardial Injury.JACC. Basic to translational science · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Highlights on Advancing Frontiers in Tissue Engineering.Tissue engineering. Part B, Reviews · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Perfluorocarbons-BasedInternational journal of nanomedicine · 2020
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Christakis ConstantinidesRadcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, Department of Cardiovascular Medicine , University of Oxford , Roosevelt Drive, Old Road Campus , Headington, Oxford OX3 7BN , U.K.ORCID http://orcid.org/0000-0001-9225-7572
Pooja BasnettApplied Biotechnology Research Group, Faculty of Science and Technology , University of Westminster , 115 New Cavendish Street , London W1W 6UW , U.K.
Barbara LukasiewiczApplied Biotechnology Research Group, Faculty of Science and Technology , University of Westminster , 115 New Cavendish Street , London W1W 6UW , U.K.
Ricardo CarnicerRadcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, Department of Cardiovascular Medicine , University of Oxford , Roosevelt Drive, Old Road Campus , Headington, Oxford OX3 7BN , U.K.
Edyta SwiderRadboud University Medical Center (Radboud UMC), Department of Tumor Immunology , Radboud Institute for Molecular Life Sciences (RIMLS) , 278, P.O. Box 9101, 6500HB Nijmegen , The Netherlands.ORCID http://orcid.org/0000-0001-8984-2009
Qasim A MajidDepartment of Myocardial Function , National Heart and Lung Institute, Imperial College London , London W12 0NN , U.K.
Mangala SrinivasRadboud University Medical Center (Radboud UMC), Department of Tumor Immunology , Radboud Institute for Molecular Life Sciences (RIMLS) , 278, P.O. Box 9101, 6500HB Nijmegen , The Netherlands.ORCID http://orcid.org/0000-0002-3835-1995
Carolyn A CarrDepartment of Physiology, Anatomy, and Genetics , University of Oxford , South Parks Road , Oxford OX1 3PT , U.K.
Ipsita RoyApplied Biotechnology Research Group, Faculty of Science and Technology , University of Westminster , 115 New Cavendish Street , London W1W 6UW , U.K.
University of Westminster · GBCentre for Human Genetics · GBRadboud University Nijmegen · NLLung Institute · USUniversity of Oxford · GB

Funding

British Heart Foundation FS/15/15/31364
6 · The paper itself

Abstract

Medium-chain length polyhydroxyalkanoates (MCL-PHAs) have demonstrated exceptional properties for cardiac tissue engineering (CTE) applications. Despite prior work on MCL-PHA/polycaprolactone (PCL) blends, optimal scaffold production and use as an alternative delivery route for controlled release of seeded cardiac progenitor cells (CPCs) in CTE applications in vivo has been lacking. We present herein applicability of MCL-PHA/PCL (95/5 wt %) blends fabricated as thin films with an improved performance compared to the neat MCL-PHA. Polymer characterization confirmed the chemical structure and composition of the synthesized scaffolds, while thermal, wettability, and mechanical properties were also investigated and compared in neat and porous counterparts. In vitro cytocompatibility studies were performed using perfluorocrown-ether-nanoparticle-labeled murine CPCs and studied using confocal microscopy and

Indexed as

AnimalsHeartMagnetic Resonance ImagingMiceMice, Inbred C57BLPolyestersPolyhydroxyalkanoatesStem CellsTissue EngineeringTissue ScaffoldspolycaprolactonePolyestersPolyhydroxyalkanoates19F magnetic resonance spectroscopy/imagingcardiac progenitor stem cellscardiac regenerationpolycaprolactonepolyhydroxyalkanoatespolymer blendspolymer scaffolds

Identifiers

PMID29965724
PMCPMC6338235
OpenAlexW2810169827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.