Evidence map›Paper›PMID 29964215›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2019

Pregnancy Results in Lasting Changes in Knee Joint Laxity.

Stacey R Chu, Elizabeth H Boyer, Bruce Beynnon, Neil A Segal

Abstract read
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Stacey R ChuCarver College of Medicine, The University of Iowa, Iowa City, Iowa.
Elizabeth H BoyerDepartment of Kinesiology, Iowa State University, Ames, Iowa.ORCID 0000-0002-5448-179X
Bruce BeynnonDepartment of Orthopaedics and Rehabilitation, The University of Vermont, Burlington, Vermont.
Neil A SegalDepartment of Epidemiology, The University of Iowa, Iowa City, IA.ORCID 0000-0002-8294-080X
University of Iowa · USIowa State University · USUniversity of Vermont · US

Funding

SHORT-TERM TRAINING: STUDENTS IN HEALTH PROF. SCHOOLST35HL007485 · NHLBI · UNIVERSITY OF IOWA · PI ROGHAIR, ROBERT D · 1985 to 2019
$4.3M
Optimizing Mobility in Elders with Knee Osteoarthritis: Gait and Power TrainingK23AG030945 · NIA · UNIVERSITY OF IOWA · PI SEGAL, NEIL A · 2007 to 2011
$862k
NHLBI NIH HHS T35 HL007485NIA NIH HHS 1K23AG030945NIA NIH HHS K23 AG030945NIH HHS 5K23AG030945NIH HHS 5T35HL007485
6 · The paper itself

Abstract

backgroundAltered joint laxity can contribute to joint dysfunction. Knee joint laxity has been shown to increase during pregnancy, but its long-term persistence is unknown.

objectiveTo determine whether pregnancy leads to lasting increases in knee joint compliance and laxity that persist longer than 4 months postpartum.

designProspective cohort study.

settingA motion analysis laboratory at an academic medical center.

participantsFifty healthy women in their first trimester of pregnancy (mean ± SD 29.2 ± 4.3 years old and baseline body mass index 26.0 ± 5.4 kg/m

interventionEnd-range knee laxity and midrange joint compliance were measured during the first trimester and 19 ± 4 weeks postpartum. Anterior-posterior and varus-valgus laxity were measured using 3-dimensional motion tracking while applying forces and moments in each respective plane using the Vermont Knee Laxity Device. Nonlinear models were constructed to assess relations between applied forces and joint translation, comparing early pregnancy with postpartum. OUTCOMES: Multiplanar knee laxity and compliance.

resultsPeak varus-valgus (20-22%; P = .001) and posterior translation (51%; P < .001) of the tibia relative to the femur decreased from baseline, with a concomitant decrease in laxity (P < .001) and compliance (P = .039) in the coronal plane and in the posterior direction in primiparous (P = .009) and multiparous (P = .014) women. For primiparous women, laxity (P < .001) and compliance (P = .009) increased in the anterior direction.

conclusionsPregnancy resulted in a lasting decrease in multiplanar knee laxity and compliance in the varus and posterior directions with an increase in anterior compliance. The effects of these changes in laxity and compliance of the passive stabilizers on knee loading patterns, articular contact stresses, and risk for osteoarthritis and other musculoskeletal disorders will require additional research. LEVEL OF EVIDENCE: II.

Indexed as

Pregnancy ComplicationsAdolescentAdultBiomechanical PhenomenaFemaleFollow-Up StudiesHumansImaging, Three-DimensionalJoint InstabilityKnee JointPregnancyPregnancy Trimester, FirstProspective StudiesRange of Motion, ArticularTime FactorsYoung Adult

Identifiers

PMID29964215
PMCPMC6320712
OpenAlexW2809852673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.