Evidence map›Paper›PMID 29964095›Full record

ArticleNeuropharmacology2018

Group I metabotropic glutamate receptors generate two types of intrinsic membrane oscillations in hippocampal oriens/alveus interneurons.

Gubbi Govindaiah, Young-Jin Kang, Hannah Elisabeth Smashey Lewis, Leeyup Chung, Ethan M Clement, Lazar John Greenfield, Edgar Garcia-Rill, Sang-Hun Lee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gubbi GovindaiahDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Young-Jin KangDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Hannah Elisabeth Smashey LewisDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Leeyup ChungDepartment of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA.
Ethan M ClementDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Lazar John GreenfieldDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA; Department of Neurology, University of Connecticut Health Center, Farmington, CT 06030, USA.
Edgar Garcia-RillCenter for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Sang-Hun LeeDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA; Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. Electronic address: sanghunlee@uams.edu.
University of Arkansas for Medical Sciences · USDuke University · USUConn Health · US

Funding

Telemedicine CoreP30GM110702 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI GARCIA-RILL, EDGAR E. · 2014 to 2018
$6.1M
NIGMS NIH HHS P30 GM110702
6 · The paper itself

Abstract

GABAergic interneurons in the hippocampus are critically involved in almost all hippocampal circuit functions including coordinated network activity. Somatostatin-expressing oriens-lacunosum moleculare (O-LM) interneurons are a major subtype of dendritically projecting interneurons in hippocampal subregions (e.g., CA1), and express group I metabotropic glutamate receptors (mGluRs), specifically mGluR

Indexed as

AnimalsBrain WavesCalcium Channels, L-TypeHippocampusInterneuronsMembrane PotentialsMembrane Transport ModulatorsMice, Inbred C57BLPeriodicityReceptor, Metabotropic Glutamate 5Receptors, Metabotropic GlutamateRyanodine Receptor Calcium Release ChannelSeizuresTissue Culture TechniquesTransient Receptor Potential ChannelsCalcium Channels, L-TypeMembrane Transport Modulatorsmetabotropic glutamate receptor type 1Receptor, Metabotropic Glutamate 5Receptors, Metabotropic GlutamateRyanodine Receptor Calcium Release ChannelTransient Receptor Potential ChannelsExcitotoxicityMetabotropic glutamate receptorsPerithreshold membrane oscillationsSeizuresSomatostatin-expressing interneurons

Identifiers

PMID29964095
PMCPMC7007965
OpenAlexW2811107557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.