ArticleeLife2018
Bidirectional encoding of motion contrast in the mouse superior colliculus.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- An inhibitory brainstem pathway reduces visual detection during background motion.Nature communications · 2026Article
- Connectivity, Computation, and Plasticity of the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- Preference-independent saliency map in the mouse superior colliculus.Communications biology · 2025Article
- Probabilistically constrained vector summation of motion direction in the mouse superior colliculus.Current biology : CB · 2025Article
- Circuit-Based Understanding of Fine Spatial Scale Clustering of Orientation Tuning in Mouse Visual Cortex.bioRxiv : the preprint server for biology · 2025Article
- Characterize neuronal responses to natural movies in the mouse superior colliculus.Frontiers in cellular neuroscience · 2025Article
- Genetically defined neuron types underlying visuomotor transformation in the superior colliculus.Nature reviews. Neuroscience · 2024Review
- Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons.Animals : an open access journal from MDPI · 2024Article
- Transformation of Motion Pattern Selectivity from Retina to Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Neural mechanisms for the localization of unexpected external motion.Nature communications · 2023Article
- Retinal input integration in excitatory and inhibitory neurons in the mouse superior colliculus in vivo.eLife · 2023Article
- Stimulus edges induce orientation tuning in superior colliculus.Nature communications · 2023Article
- Article
- Retinal waves align the concentric orientation map in mouse superior colliculus to the center of vision.Science advances · 2023Article
- What Are the Functions of the Superior Colliculus and Its Involvement in Neurologic Disorders?Neurology · 2023Article
- Synaptic properties of mouse tecto-parabigeminal pathways.Frontiers in systems neuroscience · 2023Article
- Article
- Tuning instability of non-columnar neurons in the salt-and-pepper whisker map in somatosensory cortex.Nature communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Detection of salient objects in the visual scene is a vital aspect of an animal's interactions with its environment. Here, we show that neurons in the mouse superior colliculus (SC) encode visual saliency by detecting motion contrast between stimulus center and surround. Excitatory neurons in the most superficial lamina of the SC are contextually modulated, monotonically increasing their response from suppression by the same-direction surround to maximal potentiation by an oppositely-moving surround. The degree of this potentiation declines with depth in the SC. Inhibitory neurons are suppressed by any surround at all depths. These response modulations in both neuronal populations are much more prominent to direction contrast than to phase, temporal frequency, or static orientation contrast, suggesting feature-specific saliency encoding in the mouse SC. Together, our findings provide evidence supporting locally generated feature representations in the SC, and lay the foundations towards a mechanistic and evolutionary understanding of their emergence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.