Evidence map›Paper›PMID 29963986›Full record

ArticleeLife2018

BK channel inhibition by strong extracellular acidification.

Yu Zhou, Xiao-Ming Xia, Christopher J Lingle

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Lysosomal Potassium Channels.Handbook of experimental pharmacology · 2023
    Review
  8. Mechanism of voltage sensing in CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu ZhouDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, United States.ORCID http://orcid.org/0000-0002-1623-7948
Xiao-Ming XiaDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, United States.
Christopher J LingleDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, United States.
Washington University in St. Louis · US

Funding

SLO family potassium channels: function and physiologyR35GM118114 · NIGMS · WASHINGTON UNIVERSITY · PI LINGLE, CHRISTOPHER J · 2016 to 2025
$6.9M
NIGMS NIH HHS GM118114NIGMS NIH HHS R35 GM118114
6 · The paper itself

Abstract

Mammalian BK-type voltage- and Ca

Indexed as

Amino Acid SequenceAnimalsAspartic AcidBinding SitesCalciumCytosolGene ExpressionHydrogen-Ion ConcentrationIntracellular MembranesIon Channel GatingLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLysosomesMembrane PotentialsMiceModels, MolecularOocytesAspartic AcidCalciumKcnma1 protein, mouseLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsBK channelschannel inhibitionextracellular H+K+ channelsmolecular biophysicsSlo1 channelsstructural biologyxenopus

Identifiers

PMID29963986
PMCPMC6054526
OpenAlexW2952098703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.