ArticleeLife2018
Different contributions of preparatory activity in the basal ganglia and cerebellum for self-timing.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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Who cites it
48 citing papers in PubMed.
- Self-timed movement initiation requires rapid sequential coordination of circuits in prefrontal cortex and cerebellum.bioRxiv : the preprint server for biology · 2026Article
- A brain-wide, trial- and time-dependent deterministic drive synergizes with within-trial noise to time self-initiated actions.bioRxiv : the preprint server for biology · 2026Article
- Article
- Differential cannabinergic effects on temporal perception and production.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Article
- Exploring Bidirectional Associations Between Voice Acoustics and Objective Motor Metrics in Parkinson's Disease.Brain sciences · 2025Article
- Comparison of Signals from Cerebellar Purkinje Cells and Deep Nuclei during Temporal Prediction in Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Sustained visual signals in the primate cerebellar dentate nucleus drive associative learning.Communications biology · 2025Article
- Common electrophysiological signatures of relative magnitude in both space and time.Scientific reports · 2025Article
- A cerebello-thalamo-cortical pathway transmits reward-based post-error signals for motor timing correction during learning in male mice.Nature communications · 2025Article
- Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing.Annual review of neuroscience · 2025Review
- Pallidal prototypic neuron and astrocyte activities regulate flexible reward-seeking behaviors.bioRxiv : the preprint server for biology · 2025Article
- Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques.eLife · 2025Article
- Ramping cells in the rodent medial prefrontal cortex encode time to past and future events via real Laplace transform.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Pre-supplementary Motor Cortex Mediates Learning Transfer from Perceptual to Motor Timing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Differential Formation of Motor Cortical Dynamics during Movement Preparation According to the Predictability of Go Timing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Ramping cells in rodent mPFC encode time to past and future events via real Laplace transform.bioRxiv : the preprint server for biology · 2024Article
- Keeping time and rhythm by internal simulation of sensory stimuli and behavioral actions.Science advances · 2024Article
- Temporal Information Processing in the Cerebellum and Basal Ganglia.Advances in experimental medicine and biology · 2024Review
- A purely visual adaptation to motion can differentiate between perceptual timing and interval timing.Proceedings. Biological sciences · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to flexibly adjust movement timing is important for everyday life. Although the basal ganglia and cerebellum have been implicated in monitoring of supra- and sub-second intervals, respectively, the underlying neuronal mechanism remains unclear. Here, we show that in monkeys trained to generate a self-initiated saccade at instructed timing following a visual cue, neurons in the caudate nucleus kept track of passage of time throughout the delay period, while those in the cerebellar dentate nucleus were recruited only during the last part of the delay period. Conversely, neuronal correlates of trial-by-trial variation of self-timing emerged earlier in the cerebellum than the striatum. Local inactivation of respective recording sites confirmed the difference in their relative contributions to supra- and sub-second intervals. These results suggest that the basal ganglia may measure elapsed time relative to the intended interval, while the cerebellum might be responsible for the fine adjustment of self-timing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.