Evidence map›Paper›PMID 29963752›Full record

ReviewCNS neuroscience & therapeutics2018

Social decision making in autism: On the impact of mirror neurons, motor control, and imitative behaviors.

Radwa Khalil, Richard Tindle, Thomas Boraud, Ahmed A Moustafa, Ahmed A Karim

Open access · hybridAbstract readReview
In one paragraph

Review in CNS neuroscience & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Creative therapy in health and disease: Inner vision.CNS neuroscience & therapeutics · 2024
    Review
  12. Article
  13. Viruses and autism: A Bi-mutual cause and effect.World journal of virology · 2023
    Review
  14. Invasive Computational Psychiatry.Biological psychiatry · 2023
    Review
  15. Article
  16. COMSIInternational journal of environmental research and public health · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Radwa KhalilDepartment of Psychology and Methods, Jacobs University Bremen, Bremen, Germany.ORCID 0000-0003-2632-8306
Richard TindleCanTeen, Research Evaluation and Social Policy, Sydney, NSW, Australia.ORCID 0000-0001-9661-811X
Thomas BoraudInstitute of Neurodegenerative Diseases, CNRS UMR-5293, University of Bordeaux, Bordeaux, France.ORCID 0000-0002-8942-0129
Ahmed A MoustafaMarcs Institute for Brain and Behavior, Western Sydney University, Sydney, NSW, Australia.
Ahmed A KarimDepartment of Prevention and Health Psychology, SRH Mobile University, Riedlingen, Germany.
Canteen · AUCentre National de la Recherche Scientifique · FRConstructor University · DESRH Fernhochschule – The Mobile University · DEWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Mirror Neuron System (MNS) plays a crucial role in action perception and imitative behavior, which is suggested to be impaired in Autism Spectrum Disorders (ASDs). In this review, we discuss the plausibility and empirical evidence of a neural interaction between the MNS, action perception, empathy, imitative behavior, and their impact on social decision making in ASDs. To date, there is no consensus regarding a particular theory in ASDs and its underlying mechanisms. Some theories have completely focused on social difficulties, others have emphasized sensory aspects. Based on the current studies, we suggest a multilayer neural network model including the MNS on a first layer and transforming this information to a higher layer network responsible for reasoning. Future studies with ASD participants combining behavioral tasks with neuroimaging methods and transcranial brain stimulation as well as computational modeling can help validate and complement this suggested model. Moreover, we propose applying the behavioral paradigms, and the neurophysiological markers mentioned in this review article for evaluating psychiatric treatment approaches in ASDs. The investigation of modulating effects of different treatment approaches on the neurophysiological markers of the MNS can help find specific subgroups of ASDs patients and support tailored psychiatric interventions.

Indexed as

Autistic DisorderImitative BehaviorSocial BehaviorDecision MakingHumansMirror Neuronsautism spectrum disordersbasal gangliamirror neuron systemmotor cortexsocial decision making

Identifiers

PMID29963752
PMCPMC6055683
OpenAlexW2811501154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.