Evidence map›Paper›PMID 29963649›Full record

ArticleCurrent opinion in physiology2018

Regulation of microdomain voltage-gated L-type calcium channels in cardiac health and disease.

Zunaira Shuja, Henry M Colecraft

Abstract read
In one paragraph

Article in Current opinion in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of CaInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Use of Proximity Labeling in Cardiovascular Research.JACC. Basic to translational science · 2021
    Review
  4. USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zunaira Shuja
Henry M Colecraft
Columbia University · US

Funding

L-type channel trafficking and modulation in heartR01HL121253 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Henry M. Colecraft, Steven O Marx · 2014 to 2026
$8.4M
Training in Cardiovascular Translational ResearchT32HL120826 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, TABAS, IRA A · 2014 to 2023
$4.7M
Small G-protein Regulation of Calcium ChannelsR01GM107585 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COLECRAFT, HENRY M. · 2014 to 2017
$1.2M
NHLBI NIH HHS R01 HL121253NHLBI NIH HHS T32 HL120826NIGMS NIH HHS R01 GM107585
6 · The paper itself

Abstract

Cav1.2 channels in the heart mediate excitation-contraction (E-C) coupling; tune cardiac excitability; and regulate gene expression. In ventricular myocytes, Ca

Identifiers

PMID29963649
PMCPMC6022851
OpenAlexW2777531972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.