ArticleScience advances2018
Network structure of the human musculoskeletal system shapes neural interactions on multiple time scales.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Experiment protocols for brain-body imaging of locomotion: A systematic review.Frontiers in neuroscience · 2023Pooled it
- Network integration and evolution of organ systems interactions during incremental exercise.European journal of applied physiology · 2026Article
- Ankle Kinematics and Neuromuscular Activity During the Stair-to-Ground Transition in Individuals With Acute Ankle Sprain: A Cross-Sectional Study.Journal of foot and ankle research · 2026Article
- Article
- Networks of respiratory-muscular coupling in exercise and fatigue in young adults.Physiological reports · 2026Article
- Article
- Network physiology in space: vision and perspectives on exploring physiological networks during spaceflight for the benefit of life on earth.Frontiers in network physiology · 2026Article
- Networks of intermuscular coordination distinguish male and female responses to exercise.Scientific reports · 2025Article
- A multimodal biomechanical and eye-tracking dataset of suprapostural coordination in healthy young adults.Scientific data · 2025Article
- From Myofascial Chains to the Polyconnective Network: A Novel Approach to Biomechanics and Rehabilitation Based on Graph Theory.Life (Basel, Switzerland) · 2025Article
- Assessing brain-muscle networks during motor imagery to detect covert command-following.BMC medicine · 2025Article
- Analysis of Connectivity in Electromyography Signals to Examine Neural Correlations in the Activation of Lower Leg Muscles for Postural Stability: A Pilot Study.Bioengineering (Basel, Switzerland) · 2025Article
- An inclusive anatomical network analysis of human craniocerebral topology.Journal of anatomy · 2024Article
- Dynamical network-based evaluation for neuromuscular dysfunction in stroke-induced hemiplegia during standing.Journal of neuroengineering and rehabilitation · 2024Article
- Kinematic network of joint motion provides insight on gait coordination: An observational study on Parkinson's disease.Heliyon · 2024Article
- Article
- Structural and Organizational Strategies of Locomotor Modules during Landing in Patients with Chronic Ankle Instability.Bioengineering (Basel, Switzerland) · 2024Article
- Bioprinting of inorganic-biomaterial/neural-stem-cell constructs for multiple tissue regeneration and functional recovery.National science review · 2024Article
- Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait.iScience · 2024Article
- Dissecting muscle synergies in the task space.eLife · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human motor control requires the coordination of muscle activity under the anatomical constraints imposed by the musculoskeletal system. Interactions within the central nervous system are fundamental to motor coordination, but the principles governing functional integration remain poorly understood. We used network analysis to investigate the relationship between anatomical and functional connectivity among 36 muscles. Anatomical networks were defined by the physical connections between muscles, and functional networks were based on intermuscular coherence assessed during postural tasks. We found a modular structure of functional networks that was strongly shaped by the anatomical constraints of the musculoskeletal system. Changes in postural tasks were associated with a frequency-dependent reconfiguration of the coupling between functional modules. These findings reveal distinct patterns of functional interactions between muscles involved in flexibly organizing muscle activity during postural control. Our network approach to the motor system offers a unique window into the neural circuitry driving the musculoskeletal system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.