Evidence map›Paper›PMID 29963466›Full record

ReviewEuroasian journal of hepato-gastroenterology

Liver Disease in Singapore.

Mark Muthiah, Chern H Chong, Seng G Lim

Open access · bronzeAbstract readReview
In one paragraph

Review in Euroasian journal of hepato-gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Contemporary global epidemiology of cirrhosis.Hepatology communications · 2026
    Review
  2. Public awareness and knowledge of liver health and diseases in Singapore.Journal of gastroenterology and hepatology · 2021
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 6 countries.

Mark MuthiahDivision of Gastroenterology and Hepatology, National University Health System, Singapore and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chern H ChongDivision of Gastroenterology and Hepatology, National University Health System, Singapore; Division of General Medicine, Woodlands Health Campus, Singapore.
Seng G LimDivision of Gastroenterology and Hepatology, National University Health System, Singapore and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
National University Health System · SGBristol-Myers Squibb (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver disease is a significant health issue in Singapore. In the Singapore Burden of Disease Survey, liver cancer and liver cirrhosis contributed 3.2 and 0.9% of years of life lost (YLL) out of 182,753 YLL respectively. Liver cancer was ranked 8th and liver cirrhosis was ranked 20th in YLL. Liver cancer is the 5th most common cancer in males, and has an age-adjusted rate of 17.6 per 100,000 population. The underlying etiology of liver cirrhosis is chronic hepatitis B (CHB) in 63.3%, alcohol in 11.2%, cryptogenic in 9%, and chronic hepatitis C (CHC) in 6.9%. The overall seroprevalence rate of CHB is 3.6%, while CHC is approximately 0.1%. The trend in prevalence of liver cancer is gradually reducing as is CHB. However, less is known about alcoholic liver disease and fatty liver disease and there is some evidence that the latter is increasing. Singapore has a multilayered health care system designed to provide basic health care needs to the population. There are various schemes available that provide subsidized and assisted health care for treatment of hepatitis B and C as well as liver transplantation. Health policy with regard to a national action plan has not yet been developed and there is room for health care specialists, government and nongovernment agencies to work together to tackle liver disease in Singapore.

Indexed as

Alcoholic liver diseaseBurden of diseaseChronic hepatitis BChronic hepatitis CCirrhosisHepatocellular carcinomaLiver cancerNonalcoholic fatty liver disease.

Identifiers

PMID29963466
PMCPMC6024054
OpenAlexW2805578049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.