Evidence map›Paper›PMID 29963269›Full record

ArticleOncotarget2018

Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury.

YihHuei Uen, Jin-Wun Wang, ChiaChen Wang, Yaoyun Jhang, Jo-Yun Chung, TingTing Tseng, MingJen Sheu, ShaoChen Lee

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

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  14. Computational and Bioinformatics Methods for MicroRNA Gene Prediction.Methods in molecular biology (Clifton, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

YihHuei UenDepartment of Surgery, ChiMei Hospital, Chiali, Jiali Dist., Tainan City, Taiwan.
Jin-Wun WangDepartment of Surgery, ChiMei Hospital, Chiali, Jiali Dist., Tainan City, Taiwan.
ChiaChen WangSchool of Medicine, Fu Jen Catholic University, Xinzhuang Dist., New Taipei City, Taiwan.
Yaoyun JhangSchool of Medicine, Fu Jen Catholic University, Xinzhuang Dist., New Taipei City, Taiwan.
Jo-Yun ChungSchool of Medicine, Fu Jen Catholic University, Xinzhuang Dist., New Taipei City, Taiwan.
TingTing TsengSchool of Medicine, Fu Jen Catholic University, Xinzhuang Dist., New Taipei City, Taiwan.
MingJen SheuDepartment of Hepato-Gastroenterology, ChiMei Hospital, Yongkang Dist., Tainan City, Taiwan.
ShaoChen LeeSchool of Medicine, Fu Jen Catholic University, Xinzhuang Dist., New Taipei City, Taiwan.
Fu Jen Catholic University · TWChi Mei Medical Center · TWAsia University · TWCardinal Tien Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs are small noncoding RNAs acting as novel biomarkers of various diseases and potential regulators of protein expression and functions. Syndecan-1 is the heparan sulfate proteoglycan associated with malignancy of various cancers, including breast cancer. In this study, we proposed a experimental workflow to investigate potential microRNAs that regulate SDC1 expression and affect breast cancer cell mobility. MicroRNA candidates were selected from available Gene Expression Omnibus datasets on breast malignancy. Further

Indexed as

breast cancerexosomemicroRNAsyndecan-1

Identifiers

PMID29963269
PMCPMC6021336
OpenAlexW2807967001

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.