Evidence map›Paper›PMID 29963243›Full record

ArticleOncotarget2018

Interferon-stimulated gene 20 kDa protein serum levels and clinical outcome of hepatitis B virus-related liver diseases.

Hoang Van Tong, Nghiem Xuan Hoan, Mai Thanh Binh, Dao Thanh Quyen, Christian G Meyer, Le Huu Song, Nguyen Linh Toan, Thirumalaisamy P Velavan

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. The impact of hypoxia and glycolysis on liver fibrosis.Journal of translational medicine · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. ISG20 is overexpressed in clinically relevant radioresistant oral cancer cells.International journal of clinical and experimental pathology · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hoang Van TongInstitute of Biomedicine and Pharmacy, Vietnam Military Medical University, Hanoi, Vietnam.
Nghiem Xuan HoanInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Mai Thanh BinhInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Dao Thanh QuyenInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Christian G MeyerInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Le Huu Song108 Military Central Hospital, Hanoi, Vietnam.
Nguyen Linh ToanDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.
Thirumalaisamy P VelavanInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Vietnamese - German Center of Excellence in Medical Research · VN108 Military Central Hospital · VNVietnam Military Medical University · VNUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-stimulated gene 20 kDa protein (ISG20) with 3' to 5' exonuclease activity mainly targeting single-stranded RNA plays an important role in immune responses against various infectious pathogens, including hepatitis viruses. ISG20 levels were measured by ELISA assays in sera of 339 hepatitis B-virus (HBV) infected patients and 71 healthy individuals and were correlated with clinical and laboratory parameters.

Indexed as

hepatocellular carcinomainterferon-stimulated geneISG20 expressionISG20 levelsviral hepatitis

Identifiers

PMID29963243
PMCPMC6021248
OpenAlexW2808411827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.