ArticleKorean journal of radiology
Ultrasonographic Echogenicity and Histopathologic Correlation of Thyroid Nodules in Core Needle Biopsy Specimens.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Sociodemographic and clinical predictors of malignancy in thyroid nodules: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Safety and Efficacy of Thermal Ablation for Benign Thyroid Nodules in Patients with or without Previous Thyroid Surgery.Radiology. Imaging cancer · 2025Article
- The Impact of Echogenicity Grading on the Diagnostic Performance of C-TIRADS.International journal of general medicine · 2025Article
- Clinical study on the impact of microwave ablation energy on the treatment efficacy of benign thyroid nodules.Frontiers in oncology · 2025Article
- Cancer Risk in Thyroid Nodules: An Analysis of Over 1000 Consecutive FNA Biopsies Performed in a Single Canadian Institution.Diagnostics (Basel, Switzerland) · 2024Article
- Histopathological Analysis of Thyroid Nodules with Taller-Than-Wide Shape in Adults.International journal of general medicine · 2024Article
- Orientation of the ultrasound probe to identify the taller-than-wide sign of thyroid malignancy: a registry-based study with the Thyroid Imaging Network of Korea.Ultrasonography (Seoul, Korea) · 2023Article
- Malignancy risk stratification of thyroid nodules according to echotexture and degree of hypoechogenicity: a retrospective multicenter validation study.Scientific reports · 2022Article
- Benign thyroid nodules respond to a single administration of 0.3mg recombinant human thyrotropin with highly variable volume increase.Frontiers in endocrinology · 2022Article
- Computer-Analyzed Ultrasound Predictors of the Treatment Efficacy of Radiofrequency Ablation for Benign Thyroid Nodules.World journal of surgery · 2022Article
- Usage and Diagnostic Yield of Fine-Needle Aspiration Cytology and Core Needle Biopsy in Thyroid Nodules: A Systematic Review and Meta-Analysis of Literature Published by Korean Authors.Clinical and experimental otorhinolaryngology · 2021Article
- Characteristics of Recent Articles Published in the Korean Journal of Radiology Based on the Citation Frequency.Korean journal of radiology · 2020Article
- Ultrasound malignancy risk stratification of thyroid nodules based on the degree of hypoechogenicity and echotexture.European radiology · 2020Article
- Ultrasound-Guided Core Needle Biopsy Techniques for Intermediate or Low Suspicion Thyroid Nodules: Which Method is Effective for Diagnosis?Korean journal of radiology · 2019Article
- Core needle biopsy in the management of thyroid nodules with an indeterminate fine-needle aspiration report.Gland surgery · 2019Review
- Degenerating Thyroid Nodules: Ultrasound Diagnosis, Clinical Significance, and Management.Korean journal of radiology · 2019Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine the histopathologic features associated with ultrasonographic echogenicity of thyroid nodules. Materials and Methods: This study included 95 nodules of 95 patients (76 women, 19 men; mean age 47.5 ± 12.9 years) with homogeneous echogenicity in which core needle biopsy was performed during a one year period. The nodule echogenicity was categorized into 4 grades (hyperechogenicity, isoechogenicity, mild hypoechogenicity, and marked hypoechogenicity). The biopsy specimens were evaluated by a pathologist regarding the histopathologic features of fibrosis, lymphoid infiltration, microfollicular pattern, uniform follicular pattern, and hypercellularity in nodules. We evaluated the association of each histopathologic feature among 3 categories of nodule echogenicity by multinomial regression analysis. Results: The nodule echogenicity was isoechoic in 28 (29.5%), mildly hypoechoic in 37 (38.9%), and markedly hypoechoic in 30 (31.6%), and there was no hyperechoic nodule. There was a trend of increasing frequency of fibrosis (> 30%) as nodule echogenicity decreased (isoechogenicity, 10.7%; mild hypoechogenicity, 32.4%; and marked hypoechogenicity, 80%; Conclusion: The fibrosis (> 30%) and high cellularity are independently associated with mild or marked hypoechogenicity of nodules. The knowledge of the relationship of echogenicity and histopathology of thyroid nodules could improve management of patients with thyroid nodules.
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