Evidence map›Paper›PMID 29962825›Full record

ArticleProgress in pediatric cardiology2018

Differential Response to Heart Failure Medications in Children.

Shelley D Miyamoto, Carmen C Sucharov, Kathleen C Woulfe

Open access · greenAbstract read
In one paragraph

Article in Progress in pediatric cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Potential of ATJACC. Basic to translational science · 2020
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shelley D MiyamotoDivision of Pediatric Cardiology, Department of Pediatrics, University of Colorado Denver School of Medicine and Children's Hospital Colorado, 12700 E 19 Ave, Aurora, CO USA, 80045.
Carmen C SucharovDivision of Cardiology, Department of Medicine, University of Colorado Denver School of Medicine, 12700 E 19 Ave, Aurora, CO USA 80045.
Kathleen C WoulfeDivision of Cardiology, Department of Medicine, University of Colorado Denver School of Medicine, 12700 E 19 Ave, Aurora, CO USA 80045.
University of Colorado Denver · US

Funding

Molecular and Functional Mechanisms of Pediatric Heart FailureR01HL107715 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STAUFFER, BRIAN L · 2012 to 2016
$2.8M
Myocardial Effects of PDE5 Inhibition in Single Ventricle Heart DiseaseR01HL126928 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MIYAMOTO, SHELLEY DEANNE · 2015 to 2019
$2.7M
Cardiac Beta-Adrenergic Adaptation in Pediatric Heart FailureR21HL097123 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MIYAMOTO, SHELLEY DEANNE, STAUFFER, BRIAN L · 2009 to 2010
$413k
NHLBI NIH HHS R01 HL107715NHLBI NIH HHS R01 HL126928NHLBI NIH HHS R21 HL097123
6 · The paper itself

Abstract

There have been many advances in the treatment of heart failure over the past several years. While these advancements have resulted in improved outcomes in adults with heart failure, these same treatments do not seem to be as efficacious in children with heart failure. Investigations of the failing pediatric heart suggest that there are unique phenotypic, pathologic and molecular differences that could influence how children with heart failure response to adult-based therapies. In this review, several recent studies and the potential implications of their findings on informing the future of the management of pediatric heart failure are discussed.

Indexed as

childrendilated cardiomyopathyHeart Failure

Identifiers

PMID29962825
PMCPMC6023416
OpenAlexW2785934277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.