Evidence map›Paper›PMID 29962626›Full record

ArticleAnesthesia, essays and researches

Minimum Alveolar Concentration of Desflurane for Maintaining BIS Below 50 in Children and Effect of Caudal Analgesia on it.

Jeetinder Kaur Makkar, Deepak Dwivedi, Aswini Kuberan, Balbir Kumar, Indu Bala

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In one paragraph

Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeetinder Kaur MakkarDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research Institute, Chandigarh, India.
Deepak DwivediDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research Institute, Chandigarh, India.
Aswini KuberanDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research Institute, Chandigarh, India.
Balbir KumarDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research Institute, Chandigarh, India.
Indu BalaDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research Institute, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextNeuraxial techniques have sedative properties secondary to decreased inputs from sensory and motor afferents. We hypothesized that caudal analgesia decreases the requirement of desflurane as measured by bispectral index (BIS).

aimsThis study aims to determine the minimum alveolar concentration (MAC) of desflurane for maintaining BIS below 50 (MACBIS SETTINGS AND

designThis is prospective and observational study. SUBJECTS AND

methodsThirty-nine American Society of Anesthesiologists physical status Classes I and II children in between 1 and 8 years of age undergoing elective infraumbilical surgery under general anesthesia were allocated randomly into two groups (Group C and Group D) after induction with sevoflurane and LMA insertion. In Group C, caudal block was performed with 0.75 mL/kg of 0.25% bupivacaine and BIS values were recorded after 10 min for 1 min at 10 s intervals. In Group D, BIS was recorded for desflurane for 1 min at 10 s intervals followed by a caudal block with the same dose. STATISTICAL ANALYSIS USED: Dixon up-down method with a step size of 0.5%, and probit analysis were used for analysis.

resultsA total of 39 patients were enrolled. MAC of desflurane for maintaining MACBIS

conclusionsThe use of caudal analgesia significantly reduced MAC of desflurane for maintaining MACBIS

Indexed as

Bispectral index 50caudal analgesiadesfluraneminimum alveolar concentrationpediatric infraumbilical surgeries

Identifiers

PMID29962626
PMCPMC6020569
OpenAlexW2808294671

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.