Evidence map›Paper›PMID 29962550›Full record

SynthesisBulletin of the World Health Organization2018

Cash interventions to improve clinical outcomes for pulmonary tuberculosis: systematic review and meta-analysis.

Aaron Richterman, Jonathan Steer-Massaro, Jana Jarolimova, Liem Binh Luong Nguyen, Jennifer Werdenberg, Louise C Ivers

Registry-linked trialOpen access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Bulletin of the World Health Organization, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05656287 (My Mobile Wallet), which is not on this map. Cited by 51 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05656287 naunknown statusnot on this mapstarted 2022, after this paper: background citation

My Mobile Wallet: An Intervention to Support Access to Tuberculosis Care and Medication Adherence in Rural Uganda

TypeinterventionalSponsorMbarara University of Science and TechnologyRan2022 to 2026Enrolled242ConditionsTuberculosisArmsSMS texts + incentives + Wisepill device for medication monitoring, SMS texts only + Wisepill device for medication monitoring, Wisepill device for medication monitoring only
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 5 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
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  6. Household- Versus Incentive-Based Contact Investigation for Tuberculosis in Rural South Africa: A Cluster-Randomized Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  17. Global health action · 2024
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  19. Cash transfers to enhance completion of TB screening among household contacts in rural Tanzania.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aaron RichtermanDepartment of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, United States of America (USA).
Jonathan Steer-MassaroDepartment of Obstetrics and Gynecology, Boston University School of Medicine, Boston, USA.
Jana JarolimovaDepartment of Medicine, Massachusetts General Hospital, Boston, USA.
Liem Binh Luong NguyenInfection, Antimicrobials, Modelling and Evolution, Unité Mixte de Recherche 1137, INSERM, Paris, France.
Jennifer WerdenbergDepartment of Pediatrics, Dell Children's Hospital, Austin, USA.
Louise C IversCenter for Global Health, Massachusetts General Hospital, Boston, USA.
Massachusetts General Hospital · USBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess cash transfer interventions for improving treatment outcomes of active pulmonary tuberculosis in low- and middle-income countries.

methodsWe searched PubMed®, Embase®, Cochrane Library and ClinicalTrials.gov for studies published until 4 August 2017 that reported on cash transfer interventions during the treatment of active pulmonary tuberculosis in low- and middle-income countries. Our primary outcome was a positive clinical outcome, defined as treatment success, treatment completion or microbiologic cure. Using the purchasing power parity conversion factor, we converted the amount of cash received per patient within each study into international dollars (Int$). We calculated odds ratio (OR) for the primary outcome using a random effects meta-analysis.

findingsEight studies met eligibility criteria for review inclusion. Seven studies assessed a tuberculosis-specific intervention, with average amount of cash ranging from Int$ 193-858. One study assessed a tuberculosis-sensitive intervention, with average amount of Int$ 101. Four studies included non-cash co-interventions. All studies showed better primary outcome for the intervention group than the control group. After excluding three studies with high risk of bias, patients receiving tuberculosis-specific cash transfer were more likely to have a positive clinical outcome than patients in the control groups (OR: 1.77; 95% confidence interval: 1.57-2.01).

conclusionThe evidence available suggests that patients in low- and middle-income countries receiving cash during treatment for active pulmonary tuberculosis are more likely to have a positive clinical outcome. These findings support the incorporation of cash transfer interventions into social protection schemes within tuberculosis treatment programmes.

Indexed as

Financial ManagementFinancial SupportAdultAntitubercular AgentsDeveloping CountriesFemaleHealth Care CostsHealth Services AccessibilityHumansMalePregnancyTuberculosis, PulmonaryAntitubercular Agents

Identifiers

PMID29962550
PMCPMC6022611
OpenAlexW2923331706

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.